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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YME1L1 All Species: 36.97
Human Site: Y608 Identified Species: 58.1
UniProt: Q96TA2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96TA2 NP_055078.1 773 86455 Y608 S G H A I I A Y Y T K D A M P
Chimpanzee Pan troglodytes XP_507710 903 100485 Y738 S G H A I I A Y Y T K D A M P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535172 804 89574 Y639 S G H A I I A Y Y T K D A M P
Cat Felis silvestris
Mouse Mus musculus O88967 715 80009 Y550 S G H A I I A Y Y T K D A M P
Rat Rattus norvegicus Q925S8 715 79848 Y550 S G H A I I A Y Y T K D A M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506440 766 85825 Y601 S G H A I I A Y Y T K D A M P
Chicken Gallus gallus NP_001026683 722 81118 Y557 S G H A I I A Y Y T K D A M P
Frog Xenopus laevis NP_001084592 716 79844 Y551 S G H A I I A Y Y T K D A M P
Zebra Danio Brachydanio rerio NP_001082983 722 79976 Y557 S G H A I I A Y Y T K D A M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726263 736 80633 F568 G G H A I V A F Y T K E S H P
Honey Bee Apis mellifera XP_392703 709 79559 Q555 A F L S N K D Q I H I T K S K
Nematode Worm Caenorhab. elegans P54813 676 74435 V522 D V M M G G R V A E E L I F G
Sea Urchin Strong. purpuratus XP_787399 733 80618 V560 G G H A L V A V F T K D A K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80983 717 77256 G560 G E S E V T S G A S S D L E Q
Baker's Yeast Sacchar. cerevisiae P32795 747 81753 T584 E M D K V D I T K R E C Q A R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 N.A. 82.8 N.A. 88 87.8 N.A. 88.2 75.6 76.7 72.9 N.A. 44.5 43.2 40.3 51.3
Protein Similarity: 100 85.3 N.A. 86.8 N.A. 90.5 89.9 N.A. 92.8 83.5 83.6 81.6 N.A. 61.9 60.9 59.2 68.8
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 60 0 0 60
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 13.3 6.6 80
Percent
Protein Identity: N.A. N.A. N.A. 40.2 37.2 N.A.
Protein Similarity: N.A. N.A. N.A. 59.6 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 74 0 0 74 0 14 0 0 0 67 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 7 0 7 0 0 7 7 0 0 0 0 74 0 0 0 % D
% Glu: 7 7 0 7 0 0 0 0 0 7 14 7 0 7 0 % E
% Phe: 0 7 0 0 0 0 0 7 7 0 0 0 0 7 0 % F
% Gly: 20 74 0 0 7 7 0 7 0 0 0 0 0 0 7 % G
% His: 0 0 74 0 0 0 0 0 0 7 0 0 0 7 0 % H
% Ile: 0 0 0 0 67 60 7 0 7 0 7 0 7 0 0 % I
% Lys: 0 0 0 7 0 7 0 0 7 0 74 0 7 7 7 % K
% Leu: 0 0 7 0 7 0 0 0 0 0 0 7 7 0 0 % L
% Met: 0 7 7 7 0 0 0 0 0 0 0 0 0 60 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 7 % Q
% Arg: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 7 % R
% Ser: 60 0 7 7 0 0 7 0 0 7 7 0 7 7 0 % S
% Thr: 0 0 0 0 0 7 0 7 0 74 0 7 0 0 0 % T
% Val: 0 7 0 0 14 14 0 14 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 60 67 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _