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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCF12 All Species: 14.24
Human Site: Y70 Identified Species: 31.33
UniProt: Q99081 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99081 NP_003196.1 682 72965 Y70 S G Q P S P S Y D S S R G F T
Chimpanzee Pan troglodytes XP_510436 706 75888 Y70 S G Q P S P S Y D S S R G F T
Rhesus Macaque Macaca mulatta XP_001084466 821 88777 G212 S S G S W G N G G H P S P S R
Dog Lupus familis XP_542197 632 64907 F69 G D Q N S S S F D P S R T Y G
Cat Felis silvestris
Mouse Mus musculus Q61286 706 75765 Y70 S G Q P S P S Y D S S R G F T
Rat Rattus norvegicus P51514 707 75878 Y70 S G Q P S P S Y D S S R G F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514036 657 70162 T75 A H E G L S P T P F M N S N L
Chicken Gallus gallus P30985 657 70524 L68 S G R G S F S L Y S R D S G L
Frog Xenopus laevis Q01978 658 70072 N66 P W G T E D H N G S T F D Q G
Zebra Danio Brachydanio rerio NP_999981 533 56737
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11420 710 73846 G68 S M H D T V N G G N N R Y A N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 51.7 50.4 N.A. 92 92.3 N.A. 73.1 84 52.9 43.2 N.A. 25.3 N.A. N.A. N.A.
Protein Similarity: 100 96.4 65.4 63.2 N.A. 94.4 94.6 N.A. 79.6 87.3 68.6 54.9 N.A. 40 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 40 N.A. 100 100 N.A. 0 33.3 6.6 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 53.3 N.A. 100 100 N.A. 13.3 40 13.3 0 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 0 10 0 0 46 0 0 10 10 0 0 % D
% Glu: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 10 0 10 0 37 0 % F
% Gly: 10 46 19 19 0 10 0 19 28 0 0 0 37 10 19 % G
% His: 0 10 10 0 0 0 10 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 19 % L
% Met: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 19 10 0 10 10 10 0 10 10 % N
% Pro: 10 0 0 37 0 37 10 0 10 10 10 0 10 0 0 % P
% Gln: 0 0 46 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 10 55 0 0 10 % R
% Ser: 64 10 0 10 55 19 55 0 0 55 46 10 19 10 0 % S
% Thr: 0 0 0 10 10 0 0 10 0 0 10 0 10 0 37 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 37 10 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _