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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMELX All Species: 19.39
Human Site: T76 Identified Species: 71.11
UniProt: Q99217 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99217 NP_001133.1 191 21603 T76 L S Q Q H P P T H T L Q P H H
Chimpanzee Pan troglodytes Q861X8 203 22878 T91 V S Q Q H P L T H T L Q S H H
Rhesus Macaque Macaca mulatta NP_001091983 205 23080 T90 L S Q Q H P P T H T L Q P H H
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_033796 196 21941 S77 L S Q Q H P P S H T L Q P H H
Rat Rattus norvegicus P63278 210 23465 S91 L S Q Q H P P S H T L Q P H H
Wallaby Macropus eugenll
Platypus Ornith. anatinus O97646 121 13520 S57 T P T Q H H Q S N L P Q P A Q
Chicken Gallus gallus
Frog Xenopus laevis NP_001079152 173 19709 A80 M P Q Q Q Q N A V P K L P P H
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.2 92.1 N.A. N.A. 85.1 79.5 N.A. 49.2 N.A. 42.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 86.6 92.6 N.A. N.A. 90.3 84.2 N.A. 53.4 N.A. 59.1 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 100 N.A. N.A. 93.3 93.3 N.A. 26.6 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 N.A. N.A. 100 100 N.A. 40 N.A. 33.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 0 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 86 15 0 0 72 0 0 0 0 72 86 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % K
% Leu: 58 0 0 0 0 0 15 0 0 15 72 15 0 0 0 % L
% Met: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 15 0 0 0 0 0 0 % N
% Pro: 0 29 0 0 0 72 58 0 0 15 15 0 86 15 0 % P
% Gln: 0 0 86 100 15 15 15 0 0 0 0 86 0 0 15 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 72 0 0 0 0 0 43 0 0 0 0 15 0 0 % S
% Thr: 15 0 15 0 0 0 0 43 0 72 0 0 0 0 0 % T
% Val: 15 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _