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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMELY All Species: 9.39
Human Site: Y64 Identified Species: 41.33
UniProt: Q99218 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99218 NP_001134.1 206 23250 Y64 Q S M I R P P Y S S Y G Y E P
Chimpanzee Pan troglodytes Q861X8 203 22878 Y64 Q S M I R P P Y S S Y G Y E P
Rhesus Macaque Macaca mulatta NP_001091983 205 23080 P64 Q S I R P P Y P S Y G Y E P M
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P63278 210 23465 Y64 Q S M I R Q P Y P S Y G Y E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus O97646 121 13520 S48 M P M P G Q P S V T P T Q H H
Chicken Gallus gallus
Frog Xenopus laevis NP_001079152 173 19709 N64 P V S G W L Q N P I I P A P P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 88.8 N.A. N.A. N.A. 80 N.A. 43.2 N.A. 39.8 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 93.6 N.A. N.A. N.A. 86.1 N.A. 48 N.A. 52.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 N.A. N.A. N.A. 86.6 N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 N.A. N.A. N.A. 86.6 N.A. 20 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 17 50 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 17 17 0 0 0 0 0 17 50 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 17 % H
% Ile: 0 0 17 50 0 0 0 0 0 17 17 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % L
% Met: 17 0 67 0 0 0 0 0 0 0 0 0 0 0 17 % M
% Asn: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % N
% Pro: 17 17 0 17 17 50 67 17 34 0 17 17 0 34 67 % P
% Gln: 67 0 0 0 0 34 17 0 0 0 0 0 17 0 0 % Q
% Arg: 0 0 0 17 50 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 67 17 0 0 0 0 17 50 50 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 17 0 17 0 0 0 % T
% Val: 0 17 0 0 0 0 0 0 17 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 17 50 0 17 50 17 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _