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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAD1
All Species:
32.73
Human Site:
S249
Identified Species:
55.38
UniProt:
Q99259
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99259
NP_000808.2
594
66897
S249
K
D
G
D
G
I
F
S
P
G
G
A
I
S
N
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
S249
K
D
G
D
G
I
F
S
P
G
G
A
I
S
N
Rhesus Macaque
Macaca mulatta
XP_001082995
594
66721
S249
K
D
G
D
G
I
F
S
P
G
G
A
I
S
N
Dog
Lupus familis
XP_541080
543
61384
S242
V
S
E
Q
G
H
Y
S
V
K
K
A
A
A
I
Cat
Felis silvestris
Mouse
Mus musculus
P48318
593
66630
S248
K
D
G
D
G
I
F
S
P
G
G
A
I
S
N
Rat
Rattus norvegicus
P18088
593
66622
S248
K
D
G
D
G
I
F
S
P
G
G
A
I
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514987
594
67148
S249
K
D
G
D
G
I
F
S
P
G
G
A
I
S
N
Chicken
Gallus gallus
NP_990244
590
66692
S245
K
D
G
D
G
I
F
S
P
G
G
A
I
S
N
Frog
Xenopus laevis
NP_001079270
563
64077
K241
Y
K
Y
F
P
E
V
K
T
K
G
M
A
A
V
Zebra Danio
Brachydanio rerio
NP_919400
587
66137
S242
G
D
G
D
A
L
F
S
P
G
G
A
I
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20228
510
57801
G220
C
A
A
V
C
G
L
G
T
D
H
C
I
V
V
Honey Bee
Apis mellifera
XP_391979
509
57849
G219
C
A
A
V
C
G
L
G
T
D
N
C
V
M
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784856
614
68930
G268
G
D
G
I
F
A
P
G
G
A
V
C
N
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0G4
545
60786
R249
D
Q
T
H
S
S
F
R
K
A
C
L
I
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
59.7
N.A.
97.1
97.1
N.A.
92.4
92.4
69.1
83.1
N.A.
50.6
49.8
N.A.
55
Protein Similarity:
100
100
98.4
75.5
N.A.
98.8
98.8
N.A.
96.1
96.4
77.9
91.4
N.A.
64.8
66.8
N.A.
71.3
P-Site Identity:
100
100
100
20
N.A.
100
100
N.A.
100
100
6.6
80
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
100
100
13.3
86.6
N.A.
6.6
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
0
8
8
0
0
0
15
0
65
15
15
0
% A
% Cys:
15
0
0
0
15
0
0
0
0
0
8
22
0
0
0
% C
% Asp:
8
65
0
58
0
0
0
0
0
15
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
8
0
65
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
65
0
58
15
0
22
8
58
65
0
0
8
8
% G
% His:
0
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
50
0
0
0
0
0
0
72
0
8
% I
% Lys:
50
8
0
0
0
0
0
8
8
15
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
15
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
58
% N
% Pro:
0
0
0
0
8
0
8
0
58
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
8
0
65
0
0
0
0
0
58
0
% S
% Thr:
0
0
8
0
0
0
0
0
22
0
0
0
0
0
0
% T
% Val:
8
0
0
15
0
0
8
0
8
0
8
0
8
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _