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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAD1 All Species: 30
Human Site: S287 Identified Species: 50.77
UniProt: Q99259 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99259 NP_000808.2 594 66897 S287 P K L V L F T S E Q S H Y S I
Chimpanzee Pan troglodytes Q5IS68 594 66879 S287 P K L V L F T S E Q S H Y S I
Rhesus Macaque Macaca mulatta XP_001082995 594 66721 S287 P K L V L F T S E H S H Y S I
Dog Lupus familis XP_541080 543 61384 A280 L E K N I L E A K R K G Q T P
Cat Felis silvestris
Mouse Mus musculus P48318 593 66630 S286 P K L V L F T S E H S H Y S I
Rat Rattus norvegicus P18088 593 66622 S286 P K L V L F T S E H S H Y S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514987 594 67148 S287 P K L V L F T S E H S H Y S I
Chicken Gallus gallus NP_990244 590 66692 S283 P K L V L F T S E H S H Y S I
Frog Xenopus laevis NP_001079270 563 64077 L279 F G S E N V I L I K S D E R G
Zebra Danio Brachydanio rerio NP_919400 587 66137 S280 P R L V L F T S E H S H Y S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20228 510 57801 N258 G D I P F F V N A T A G T T V
Honey Bee Apis mellifera XP_391979 509 57849 N257 G H I P F F V N A T A G T T V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784856 614 68930 Q306 L V M F T S E Q S H F S I K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0G4 545 60786 D287 L E E A I S H D L A K G F I P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.9 59.7 N.A. 97.1 97.1 N.A. 92.4 92.4 69.1 83.1 N.A. 50.6 49.8 N.A. 55
Protein Similarity: 100 100 98.4 75.5 N.A. 98.8 98.8 N.A. 96.1 96.4 77.9 91.4 N.A. 64.8 66.8 N.A. 71.3
P-Site Identity: 100 100 93.3 0 N.A. 93.3 93.3 N.A. 93.3 93.3 6.6 86.6 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 93.3 40 N.A. 93.3 93.3 N.A. 93.3 93.3 13.3 93.3 N.A. 40 40 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 22.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 15 8 15 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 8 0 0 0 8 0 0 0 % D
% Glu: 0 15 8 8 0 0 15 0 58 0 0 0 8 0 0 % E
% Phe: 8 0 0 8 15 72 0 0 0 0 8 0 8 0 0 % F
% Gly: 15 8 0 0 0 0 0 0 0 0 0 29 0 0 8 % G
% His: 0 8 0 0 0 0 8 0 0 50 0 58 0 0 0 % H
% Ile: 0 0 15 0 15 0 8 0 8 0 0 0 8 8 58 % I
% Lys: 0 50 8 0 0 0 0 0 8 8 15 0 0 8 0 % K
% Leu: 22 0 58 0 58 8 0 8 8 0 0 0 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 15 0 0 0 0 0 0 0 % N
% Pro: 58 0 0 15 0 0 0 0 0 0 0 0 0 0 15 % P
% Gln: 0 0 0 0 0 0 0 8 0 15 0 0 8 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 8 0 0 0 8 8 % R
% Ser: 0 0 8 0 0 15 0 58 8 0 65 8 0 58 0 % S
% Thr: 0 0 0 0 8 0 58 0 0 15 0 0 15 22 0 % T
% Val: 0 8 0 58 0 8 15 0 0 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _