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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAD1 All Species: 16.97
Human Site: S72 Identified Species: 28.72
UniProt: Q99259 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99259 NP_000808.2 594 66897 S72 S A F K E R Q S S K N L L S C
Chimpanzee Pan troglodytes Q5IS68 594 66879 S72 S A F K E R Q S S K N L L S C
Rhesus Macaque Macaca mulatta XP_001082995 594 66721 S72 S A F K E R Q S S K N L L S C
Dog Lupus familis XP_541080 543 61384 L74 L Q V A N I L L H Y I K K T F
Cat Felis silvestris
Mouse Mus musculus P48318 593 66630 S72 A F R E R Q S S K N L L S C E
Rat Rattus norvegicus P18088 593 66622 S72 A F R E R Q A S K N L L S C E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514987 594 67148 S72 S A F K E R Q S S K N Q L A C
Chicken Gallus gallus NP_990244 590 66692 A74 Q S S K N L L A C E N S E R E
Frog Xenopus laevis NP_001079270 563 64077 D72 F S N L F A R D L L P A K N G
Zebra Danio Brachydanio rerio NP_919400 587 66137 Q72 F K E S A K N Q M S C D N N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20228 510 57801 D53 D F V K A T N D R N E K V L D
Honey Bee Apis mellifera XP_391979 509 57849 D52 D F I K S T N D R N A K V L D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784856 614 68930 R83 R L L Q D R R R L V D R T V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0G4 545 60786 Y80 V D F I A D Y Y K N L Q D S P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.9 59.7 N.A. 97.1 97.1 N.A. 92.4 92.4 69.1 83.1 N.A. 50.6 49.8 N.A. 55
Protein Similarity: 100 100 98.4 75.5 N.A. 98.8 98.8 N.A. 96.1 96.4 77.9 91.4 N.A. 64.8 66.8 N.A. 71.3
P-Site Identity: 100 100 100 0 N.A. 13.3 13.3 N.A. 86.6 13.3 0 0 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 6.6 N.A. 33.3 33.3 N.A. 93.3 33.3 20 13.3 N.A. 13.3 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 22.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 29 0 8 22 8 8 8 0 0 8 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 8 0 0 15 29 % C
% Asp: 15 8 0 0 8 8 0 22 0 0 8 8 8 0 15 % D
% Glu: 0 0 8 15 29 0 0 0 0 8 8 0 8 0 29 % E
% Phe: 15 29 36 0 8 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 8 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 8 0 50 0 8 0 0 22 29 0 22 15 0 0 % K
% Leu: 8 8 8 8 0 8 15 8 15 8 22 36 29 15 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 15 0 22 0 0 36 36 0 8 15 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % P
% Gln: 8 8 0 8 0 15 29 8 0 0 0 15 0 0 0 % Q
% Arg: 8 0 15 0 15 36 15 8 15 0 0 8 0 8 0 % R
% Ser: 29 15 8 8 8 0 8 43 29 8 0 8 15 29 8 % S
% Thr: 0 0 0 0 0 15 0 0 0 0 0 0 8 8 0 % T
% Val: 8 0 15 0 0 0 0 0 0 8 0 0 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 8 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _