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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAD1
All Species:
10.91
Human Site:
S78
Identified Species:
18.46
UniProt:
Q99259
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99259
NP_000808.2
594
66897
S78
Q
S
S
K
N
L
L
S
C
E
N
S
D
R
D
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
S78
Q
S
S
K
N
L
L
S
C
E
N
S
D
R
D
Rhesus Macaque
Macaca mulatta
XP_001082995
594
66721
S78
Q
S
S
K
N
L
L
S
C
E
N
S
D
R
D
Dog
Lupus familis
XP_541080
543
61384
T80
L
L
H
Y
I
K
K
T
F
D
V
K
T
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P48318
593
66630
C78
S
S
K
N
L
L
S
C
E
N
S
D
Q
G
A
Rat
Rattus norvegicus
P18088
593
66622
C78
A
S
K
N
L
L
S
C
E
N
S
D
P
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514987
594
67148
A78
Q
S
S
K
N
Q
L
A
C
E
N
S
E
Q
D
Chicken
Gallus gallus
NP_990244
590
66692
R80
L
A
C
E
N
S
E
R
E
A
R
F
R
R
T
Frog
Xenopus laevis
NP_001079270
563
64077
N78
R
D
L
L
P
A
K
N
G
K
N
S
Q
C
S
Zebra Danio
Brachydanio rerio
NP_919400
587
66137
N78
N
Q
M
S
C
D
N
N
E
R
F
T
R
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20228
510
57801
L59
N
D
R
N
E
K
V
L
D
F
H
H
P
E
D
Honey Bee
Apis mellifera
XP_391979
509
57849
L58
N
D
R
N
A
K
V
L
D
F
H
H
P
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784856
614
68930
V89
R
R
L
V
D
R
T
V
S
E
G
Q
L
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0G4
545
60786
S86
Y
Y
K
N
L
Q
D
S
P
Q
D
F
P
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
59.7
N.A.
97.1
97.1
N.A.
92.4
92.4
69.1
83.1
N.A.
50.6
49.8
N.A.
55
Protein Similarity:
100
100
98.4
75.5
N.A.
98.8
98.8
N.A.
96.1
96.4
77.9
91.4
N.A.
64.8
66.8
N.A.
71.3
P-Site Identity:
100
100
100
0
N.A.
13.3
13.3
N.A.
73.3
13.3
13.3
0
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
20
20
N.A.
93.3
26.6
33.3
20
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
8
0
8
0
8
0
0
0
0
15
% A
% Cys:
0
0
8
0
8
0
0
15
29
0
0
0
0
8
0
% C
% Asp:
0
22
0
0
8
8
8
0
15
8
8
15
22
8
43
% D
% Glu:
0
0
0
8
8
0
8
0
29
36
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
15
8
15
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
8
0
0
15
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
15
15
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
0
0
22
29
0
22
15
0
0
8
0
8
0
8
0
% K
% Leu:
15
8
15
8
22
36
29
15
0
0
0
0
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
36
36
0
8
15
0
15
36
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
0
0
0
29
0
0
% P
% Gln:
29
8
0
0
0
15
0
0
0
8
0
8
15
8
0
% Q
% Arg:
15
8
15
0
0
8
0
8
0
8
8
0
15
36
0
% R
% Ser:
8
43
29
8
0
8
15
29
8
0
15
36
0
8
8
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
8
8
0
8
% T
% Val:
0
0
0
8
0
0
15
8
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _