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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAD1
All Species:
26.06
Human Site:
Y336
Identified Species:
44.1
UniProt:
Q99259
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99259
NP_000808.2
594
66897
Y336
L
E
A
K
Q
K
G
Y
V
P
F
Y
V
N
A
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
Y336
L
E
A
K
Q
K
G
Y
V
P
F
Y
V
N
A
Rhesus Macaque
Macaca mulatta
XP_001082995
594
66721
Y336
L
E
A
K
Q
K
G
Y
V
P
F
Y
V
N
A
Dog
Lupus familis
XP_541080
543
61384
E313
H
A
I
A
D
I
C
E
T
H
R
L
W
M
H
Cat
Felis silvestris
Mouse
Mus musculus
P48318
593
66630
Y335
L
D
A
K
Q
K
G
Y
V
P
L
Y
V
N
A
Rat
Rattus norvegicus
P18088
593
66622
F335
L
D
A
K
Q
K
G
F
V
P
L
Y
V
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514987
594
67148
Y336
L
E
A
K
Q
K
G
Y
V
P
L
Y
V
N
A
Chicken
Gallus gallus
NP_990244
590
66692
Y332
L
E
A
K
Q
K
G
Y
V
P
L
F
V
N
A
Frog
Xenopus laevis
NP_001079270
563
64077
A312
Y
I
P
L
Y
V
N
A
T
A
G
T
T
V
Y
Zebra Danio
Brachydanio rerio
NP_919400
587
66137
Y329
I
D
A
K
Q
K
G
Y
V
P
L
F
V
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20228
510
57801
A291
C
W
M
H
I
D
A
A
W
G
G
G
L
L
M
Honey Bee
Apis mellifera
XP_391979
509
57849
A290
L
W
L
H
I
D
A
A
W
G
G
G
L
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784856
614
68930
E353
Q
Q
A
I
G
R
G
E
K
P
F
F
V
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0G4
545
60786
G323
G
N
I
A
K
K
Y
G
I
W
L
H
V
D
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
59.7
N.A.
97.1
97.1
N.A.
92.4
92.4
69.1
83.1
N.A.
50.6
49.8
N.A.
55
Protein Similarity:
100
100
98.4
75.5
N.A.
98.8
98.8
N.A.
96.1
96.4
77.9
91.4
N.A.
64.8
66.8
N.A.
71.3
P-Site Identity:
100
100
100
0
N.A.
86.6
80
N.A.
93.3
86.6
0
73.3
N.A.
0
6.6
N.A.
46.6
P-Site Similarity:
100
100
100
0
N.A.
93.3
93.3
N.A.
93.3
93.3
0
93.3
N.A.
6.6
13.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
65
15
0
0
15
22
0
8
0
0
0
0
72
% A
% Cys:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
0
0
8
15
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
36
0
0
0
0
0
15
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
29
22
0
0
0
% F
% Gly:
8
0
0
0
8
0
65
8
0
15
22
15
0
0
0
% G
% His:
8
0
0
15
0
0
0
0
0
8
0
8
0
0
8
% H
% Ile:
8
8
15
8
15
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
58
8
65
0
0
8
0
0
0
0
0
0
% K
% Leu:
58
0
8
8
0
0
0
0
0
0
43
8
15
15
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
0
0
65
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
65
0
0
0
0
0
% P
% Gln:
8
8
0
0
58
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
15
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
58
0
0
0
72
8
0
% V
% Trp:
0
15
0
0
0
0
0
0
15
8
0
0
8
0
0
% W
% Tyr:
8
0
0
0
8
0
8
50
0
0
0
43
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _