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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAD1
All Species:
38.18
Human Site:
Y489
Identified Species:
64.62
UniProt:
Q99259
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99259
NP_000808.2
594
66897
Y489
K
C
L
E
L
A
E
Y
L
Y
A
K
I
K
N
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
Y489
K
C
L
E
L
A
E
Y
L
Y
A
K
I
K
N
Rhesus Macaque
Macaca mulatta
XP_001082995
594
66721
Y489
K
C
L
E
L
A
E
Y
L
Y
A
K
I
K
N
Dog
Lupus familis
XP_541080
543
61384
D447
Y
K
V
L
K
K
K
D
N
F
K
L
V
F
D
Cat
Felis silvestris
Mouse
Mus musculus
P48318
593
66630
Y488
K
C
L
E
L
A
D
Y
L
Y
A
K
I
K
N
Rat
Rattus norvegicus
P18088
593
66622
Y488
K
C
L
E
L
A
E
Y
L
Y
A
K
I
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514987
594
67148
Y489
K
C
L
E
L
A
E
Y
L
Y
A
K
I
K
N
Chicken
Gallus gallus
NP_990244
590
66692
Y485
K
C
L
E
L
A
E
Y
L
Y
T
K
I
K
N
Frog
Xenopus laevis
NP_001079270
563
64077
Y458
K
C
L
E
L
G
E
Y
L
Y
S
K
I
Y
N
Zebra Danio
Brachydanio rerio
NP_919400
587
66137
Y482
R
C
L
E
L
S
E
Y
L
Y
N
K
I
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20228
510
57801
E425
F
H
L
I
L
E
P
E
C
V
N
V
S
F
W
Honey Bee
Apis mellifera
XP_391979
509
57849
E424
Y
Y
L
I
L
E
P
E
M
V
N
V
C
F
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784856
614
68930
Y506
K
L
F
D
L
A
Q
Y
L
V
D
R
I
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0G4
545
60786
V458
A
Q
D
P
S
F
E
V
V
T
T
R
Y
F
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
59.7
N.A.
97.1
97.1
N.A.
92.4
92.4
69.1
83.1
N.A.
50.6
49.8
N.A.
55
Protein Similarity:
100
100
98.4
75.5
N.A.
98.8
98.8
N.A.
96.1
96.4
77.9
91.4
N.A.
64.8
66.8
N.A.
71.3
P-Site Identity:
100
100
100
0
N.A.
93.3
100
N.A.
100
93.3
80
80
N.A.
13.3
13.3
N.A.
46.6
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
100
93.3
86.6
93.3
N.A.
13.3
20
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
58
0
0
0
0
43
0
0
0
8
% A
% Cys:
0
65
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
0
0
8
8
0
0
8
8
0
0
8
0
0
0
8
% D
% Glu:
0
0
0
65
0
15
65
15
0
0
0
0
0
0
0
% E
% Phe:
8
0
8
0
0
8
0
0
0
8
0
0
0
29
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
0
0
0
0
0
72
0
0
% I
% Lys:
65
8
0
0
8
8
8
0
0
0
8
65
0
65
0
% K
% Leu:
0
8
79
8
86
0
0
0
72
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
22
0
0
0
65
% N
% Pro:
0
0
0
8
0
0
15
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
0
0
0
8
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
15
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
8
8
22
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
15
8
0
0
0
0
0
72
0
65
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _