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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX2
All Species:
30.61
Human Site:
S433
Identified Species:
48.1
UniProt:
Q99424
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99424
NP_003491.1
681
76827
S433
L
V
T
K
L
S
A
S
C
T
Y
E
G
E
N
Chimpanzee
Pan troglodytes
XP_001174257
681
76735
S433
L
V
T
K
L
L
A
S
C
T
Y
E
G
E
N
Rhesus Macaque
Macaca mulatta
XP_001102134
660
74475
S417
I
Y
V
N
F
T
P
S
C
T
F
E
G
E
N
Dog
Lupus familis
XP_541826
664
74511
S433
L
V
S
R
V
T
A
S
C
T
Y
E
G
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXD1
681
76874
S433
L
V
T
Q
A
I
A
S
C
T
Y
E
G
E
N
Rat
Rattus norvegicus
P97562
681
76780
S433
L
V
A
R
A
T
A
S
C
T
Y
E
G
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514051
633
70993
R405
V
M
M
L
Q
T
A
R
F
L
M
K
S
Y
N
Chicken
Gallus gallus
XP_414406
675
75475
S433
L
Y
T
K
I
L
A
S
C
I
Y
E
G
E
N
Frog
Xenopus laevis
NP_001084533
670
74874
S428
L
Y
T
K
V
T
A
S
C
T
Y
E
G
E
N
Zebra Danio
Brachydanio rerio
NP_001005933
660
74026
T417
I
Y
V
T
F
T
P
T
C
T
Y
E
G
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
V430
I
Y
G
M
T
T
A
V
C
T
Y
E
G
E
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34355
659
74696
A429
L
Y
T
C
S
V
G
A
C
T
Y
E
G
E
N
Sea Urchin
Strong. purpuratus
XP_783450
682
76709
A438
L
Y
G
T
A
A
P
A
S
T
Y
E
G
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65202
664
74283
A420
L
F
A
V
Y
V
P
A
C
T
Y
E
G
D
N
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
Q484
G
Y
D
D
W
V
V
Q
C
T
W
E
G
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
44.3
76.6
N.A.
73.2
73.7
N.A.
40.5
57.5
54.6
44.4
N.A.
36.1
N.A.
32.8
43.2
Protein Similarity:
100
99.5
62.4
86
N.A.
84.8
83.8
N.A.
58.4
74
69.9
63.8
N.A.
52.7
N.A.
55
60.1
P-Site Identity:
100
93.3
46.6
73.3
N.A.
80
73.3
N.A.
13.3
73.3
80
46.6
N.A.
53.3
N.A.
60
46.6
P-Site Similarity:
100
93.3
66.6
100
N.A.
86.6
86.6
N.A.
40
80
93.3
66.6
N.A.
66.6
N.A.
66.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.6
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
20
7
60
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
87
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
0
0
0
0
0
0
0
0
14
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
94
0
80
0
% E
% Phe:
0
7
0
0
14
0
0
0
7
0
7
0
0
0
0
% F
% Gly:
7
0
14
0
0
0
7
0
0
0
0
0
94
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
7
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
27
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
67
0
0
7
14
14
0
0
0
7
0
0
0
0
0
% L
% Met:
0
7
7
7
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
100
% N
% Pro:
0
0
0
0
0
0
27
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
14
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
7
7
0
54
7
0
0
0
7
0
0
% S
% Thr:
0
0
40
14
7
47
0
7
0
87
0
0
0
0
0
% T
% Val:
7
34
14
7
14
20
7
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
54
0
0
7
0
0
0
0
0
80
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _