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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACOX2 All Species: 15.15
Human Site: S461 Identified Species: 23.81
UniProt: Q99424 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99424 NP_003491.1 681 76827 S461 S Y L Q T Q M S P G S T P Q R
Chimpanzee Pan troglodytes XP_001174257 681 76735 S461 S Y L Q T Q M S P G S T P Q R
Rhesus Macaque Macaca mulatta XP_001102134 660 74475 G445 S Y D Q V H S G K L V C G M V
Dog Lupus familis XP_541826 664 74511 S461 N Y L Q V H G S L G S T S Q M
Cat Felis silvestris
Mouse Mus musculus Q9QXD1 681 76874 S461 S Y L Q A Q V S P G S I P Q K
Rat Rattus norvegicus P97562 681 76780 S461 S Y L Q A Q A S P G A T P Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514051 633 70993 Q433 Y L N D L P S Q R I Q P Q Q V
Chicken Gallus gallus XP_414406 675 75475 G461 C F S A A S A G Q P V P P S V
Frog Xenopus laevis NP_001084533 670 74874 G456 C Y A A A Q S G Q S L P Q S V
Zebra Danio Brachydanio rerio NP_001005933 660 74026 G445 S Y K Q A R A G Q Q L T G I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KML2 669 74269 G458 V Y G Q A L N G E K L V P T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34355 659 74696 G457 A A A K A E K G E E M A P L V
Sea Urchin Strong. purpuratus XP_783450 682 76709 K466 V A R Q A G S K D K L V G C A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65202 664 74283 G448 T V A Q L G S G K V P V G T T
Baker's Yeast Sacchar. cerevisiae P13711 748 84024 K512 K F I D S A T K G R F D N T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 44.3 76.6 N.A. 73.2 73.7 N.A. 40.5 57.5 54.6 44.4 N.A. 36.1 N.A. 32.8 43.2
Protein Similarity: 100 99.5 62.4 86 N.A. 84.8 83.8 N.A. 58.4 74 69.9 63.8 N.A. 52.7 N.A. 55 60.1
P-Site Identity: 100 100 20 53.3 N.A. 73.3 73.3 N.A. 6.6 6.6 13.3 26.6 N.A. 20 N.A. 6.6 6.6
P-Site Similarity: 100 100 20 60 N.A. 86.6 86.6 N.A. 6.6 13.3 13.3 33.3 N.A. 20 N.A. 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 38.6 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 56.9 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 20 14 54 7 20 0 0 0 7 7 0 0 7 % A
% Cys: 14 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % C
% Asp: 0 0 7 14 0 0 0 0 7 0 0 7 0 0 0 % D
% Glu: 0 0 0 0 0 7 0 0 14 7 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 7 0 0 14 7 47 7 34 0 0 27 0 0 % G
% His: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 7 0 7 0 7 0 % I
% Lys: 7 0 7 7 0 0 7 14 14 14 0 0 0 0 14 % K
% Leu: 0 7 34 0 14 7 0 0 7 7 27 0 0 7 7 % L
% Met: 0 0 0 0 0 0 14 0 0 0 7 0 0 7 7 % M
% Asn: 7 0 7 0 0 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 7 0 0 27 7 7 20 47 0 0 % P
% Gln: 0 0 0 67 0 34 0 7 20 7 7 0 14 40 0 % Q
% Arg: 0 0 7 0 0 7 0 0 7 7 0 0 0 0 14 % R
% Ser: 40 0 7 0 7 7 34 34 0 7 27 0 7 14 0 % S
% Thr: 7 0 0 0 14 0 7 0 0 0 0 34 0 20 7 % T
% Val: 14 7 0 0 14 0 7 0 0 7 14 20 0 0 47 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _