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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX2
All Species:
9.09
Human Site:
Y27
Identified Species:
14.29
UniProt:
Q99424
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99424
NP_003491.1
681
76827
Y27
P
D
I
E
S
E
R
Y
M
Q
S
F
D
V
E
Chimpanzee
Pan troglodytes
XP_001174257
681
76735
Y27
P
D
I
E
S
E
R
Y
M
Q
S
F
D
V
E
Rhesus Macaque
Macaca mulatta
XP_001102134
660
74475
P27
T
H
I
L
D
G
S
P
E
N
T
R
R
R
R
Dog
Lupus familis
XP_541826
664
74511
Y27
P
D
I
E
S
E
R
Y
I
Q
S
F
N
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXD1
681
76874
H27
P
D
I
D
S
E
W
H
S
P
S
F
S
V
E
Rat
Rattus norvegicus
P97562
681
76780
H27
P
D
I
D
S
E
R
H
S
P
S
F
S
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514051
633
70993
R28
E
D
M
N
F
L
D
R
T
N
R
Y
E
L
A
Chicken
Gallus gallus
XP_414406
675
75475
L27
P
D
L
A
S
E
R
L
T
A
S
F
C
V
P
Frog
Xenopus laevis
NP_001084533
670
74874
L31
P
S
F
C
V
E
T
L
T
N
L
L
D
G
S
Zebra Danio
Brachydanio rerio
NP_001005933
660
74026
A27
T
N
V
L
D
G
G
A
E
K
T
N
R
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
W28
P
R
E
F
S
V
L
W
A
G
G
E
E
R
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34355
659
74696
A31
F
D
T
D
A
L
A
A
V
F
H
G
G
E
D
Sea Urchin
Strong. purpuratus
XP_783450
682
76709
E30
P
D
I
A
E
E
R
E
N
A
K
F
D
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65202
664
74283
R29
K
I
V
W
A
G
S
R
H
A
F
E
V
S
D
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
I29
K
E
R
A
D
S
K
I
K
V
D
Q
V
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
44.3
76.6
N.A.
73.2
73.7
N.A.
40.5
57.5
54.6
44.4
N.A.
36.1
N.A.
32.8
43.2
Protein Similarity:
100
99.5
62.4
86
N.A.
84.8
83.8
N.A.
58.4
74
69.9
63.8
N.A.
52.7
N.A.
55
60.1
P-Site Identity:
100
100
6.6
86.6
N.A.
60
66.6
N.A.
6.6
53.3
20
0
N.A.
13.3
N.A.
6.6
46.6
P-Site Similarity:
100
100
13.3
100
N.A.
73.3
80
N.A.
33.3
60
20
26.6
N.A.
26.6
N.A.
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.6
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
14
0
7
14
7
20
0
0
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
60
0
20
20
0
7
0
0
0
7
0
27
0
14
% D
% Glu:
7
7
7
20
7
54
0
7
14
0
0
14
14
7
34
% E
% Phe:
7
0
7
7
7
0
0
0
0
7
7
47
0
0
7
% F
% Gly:
0
0
0
0
0
20
7
0
0
7
7
7
7
7
0
% G
% His:
0
7
0
0
0
0
0
14
7
0
7
0
0
0
0
% H
% Ile:
0
7
47
0
0
0
0
7
7
0
0
0
0
0
7
% I
% Lys:
14
0
0
0
0
0
7
0
7
7
7
0
0
0
0
% K
% Leu:
0
0
7
14
0
14
7
14
0
0
7
7
0
7
0
% L
% Met:
0
0
7
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
7
20
0
7
7
7
0
% N
% Pro:
60
0
0
0
0
0
0
7
0
14
0
0
0
7
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
7
0
0
0
% Q
% Arg:
0
7
7
0
0
0
40
14
0
0
7
7
14
20
14
% R
% Ser:
0
7
0
0
47
7
14
0
14
0
40
0
14
7
7
% S
% Thr:
14
0
7
0
0
0
7
0
20
0
14
0
0
0
7
% T
% Val:
0
0
14
0
7
7
0
0
7
7
0
0
14
40
0
% V
% Trp:
0
0
0
7
0
0
7
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
20
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _