KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCB
All Species:
15.76
Human Site:
Y107
Identified Species:
43.33
UniProt:
Q99426
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99426
NP_001272.2
244
27326
Y107
D
V
S
R
V
E
K
Y
T
I
S
Q
E
A
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102227
241
26328
Y107
D
V
S
R
V
E
K
Y
T
I
S
Q
E
A
Y
Dog
Lupus familis
XP_533685
236
26316
T107
D
V
S
K
W
G
Q
T
D
M
A
D
S
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1E6
244
27367
Y107
D
V
S
K
V
E
K
Y
E
I
S
P
E
A
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518078
301
32806
Y107
D
L
S
R
V
E
K
Y
E
I
S
Q
S
A
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121902
244
28235
S109
N
V
E
K
F
E
I
S
E
E
E
Y
A
K
R
Nematode Worm
Caenorhab. elegans
Q20728
229
25422
M102
S
M
V
E
K
Y
E
M
S
D
D
T
Y
G
K
Sea Urchin
Strong. purpuratus
XP_780937
251
27859
K109
E
D
V
S
R
V
E
K
F
E
I
S
K
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53904
254
28335
V107
E
G
I
P
S
M
E
V
I
S
E
E
D
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.6
89.3
N.A.
89.3
N.A.
N.A.
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
51.6
42.2
56.1
Protein Similarity:
100
N.A.
88.5
93
N.A.
94.6
N.A.
N.A.
65.4
N.A.
N.A.
N.A.
N.A.
N.A.
68.8
59.4
72.1
P-Site Identity:
100
N.A.
100
20
N.A.
80
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
0
0
P-Site Similarity:
100
N.A.
100
46.6
N.A.
86.6
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
12
45
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
56
12
0
0
0
0
0
0
12
12
12
12
12
12
0
% D
% Glu:
23
0
12
12
0
56
34
0
34
23
23
12
34
0
12
% E
% Phe:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
12
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
12
0
12
45
12
0
0
0
0
% I
% Lys:
0
0
0
34
12
0
45
12
0
0
0
0
12
12
12
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
12
0
0
0
12
0
12
0
12
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
34
0
0
0
% Q
% Arg:
0
0
0
34
12
0
0
0
0
0
0
0
0
0
23
% R
% Ser:
12
0
56
12
12
0
0
12
12
12
45
12
23
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
23
0
0
12
0
0
0
% T
% Val:
0
56
23
0
45
12
0
12
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
45
0
0
0
12
12
12
45
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _