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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCB
All Species:
11.52
Human Site:
Y114
Identified Species:
31.67
UniProt:
Q99426
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99426
NP_001272.2
244
27326
Y114
Y
T
I
S
Q
E
A
Y
D
Q
R
Q
D
T
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102227
241
26328
Y114
Y
T
I
S
Q
E
A
Y
D
Q
R
Q
G
T
G
Dog
Lupus familis
XP_533685
236
26316
R114
T
D
M
A
D
S
V
R
S
F
L
K
R
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1E6
244
27367
Y114
Y
E
I
S
P
E
A
Y
E
R
R
Q
N
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518078
301
32806
Y114
Y
E
I
S
Q
S
A
Y
E
K
R
P
D
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121902
244
28235
R116
S
E
E
E
Y
A
K
R
T
D
T
V
K
A
F
Nematode Worm
Caenorhab. elegans
Q20728
229
25422
K109
M
S
D
D
T
Y
G
K
R
T
D
S
V
R
A
Sea Urchin
Strong. purpuratus
XP_780937
251
27859
E116
K
F
E
I
S
K
D
E
Y
D
K
R
A
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53904
254
28335
L114
V
I
S
E
E
D
Y
L
R
R
D
Q
S
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.6
89.3
N.A.
89.3
N.A.
N.A.
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
51.6
42.2
56.1
Protein Similarity:
100
N.A.
88.5
93
N.A.
94.6
N.A.
N.A.
65.4
N.A.
N.A.
N.A.
N.A.
N.A.
68.8
59.4
72.1
P-Site Identity:
100
N.A.
86.6
0
N.A.
66.6
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
100
N.A.
86.6
26.6
N.A.
86.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
45
0
0
0
0
0
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
12
12
12
12
0
23
23
23
0
23
12
0
% D
% Glu:
0
34
23
23
12
34
0
12
23
0
0
0
0
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
45
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
12
12
12
0
12
12
12
12
0
12
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
12
% L
% Met:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
34
0
0
0
0
23
0
45
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
23
23
23
45
12
12
12
0
% R
% Ser:
12
12
12
45
12
23
0
0
12
0
0
12
12
23
12
% S
% Thr:
12
23
0
0
12
0
0
0
12
12
12
0
0
34
0
% T
% Val:
12
0
0
0
0
0
12
0
0
0
0
12
12
12
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
45
0
0
0
12
12
12
45
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _