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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NELL2 All Species: 30.91
Human Site: Y437 Identified Species: 85
UniProt: Q99435 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99435 NP_001138579.1 816 91346 Y437 A L R E D N A Y C E D I D E C
Chimpanzee Pan troglodytes XP_001173867 839 92909 Y459 S V Q G D S A Y C E D I D E C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851616 816 91203 Y437 A L R E D N A Y C E D I D E C
Cat Felis silvestris
Mouse Mus musculus Q61220 816 91146 Y437 A L R E D N A Y C E D I D E C
Rat Rattus norvegicus Q62918 816 90934 Y437 A L R E D N A Y C E D I D E C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90827 816 90950 Y437 A L R E D N A Y C E D V D E C
Frog Xenopus laevis Q7ZXL5 814 91034 Y435 A L R E D N A Y C E D I D E C
Zebra Danio Brachydanio rerio A1A5Y0 811 89123 Y435 P L R L D S A Y C E D I D E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O77469 728 79302 N392 T G F C E D V N E C Q Q G V C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.5 N.A. 98.1 N.A. 92.8 93.3 N.A. N.A. 87.5 81.3 65.4 N.A. N.A. N.A. 21.5 N.A.
Protein Similarity: 100 70 N.A. 99.1 N.A. 96.1 97.1 N.A. N.A. 93.1 89.8 80 N.A. N.A. N.A. 34.4 N.A.
P-Site Identity: 100 66.6 N.A. 100 N.A. 100 100 N.A. N.A. 93.3 100 80 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 86.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 12 0 0 0 0 89 12 0 0 0 0 100 % C
% Asp: 0 0 0 0 89 12 0 0 0 0 89 0 89 0 0 % D
% Glu: 0 0 0 67 12 0 0 0 12 89 0 0 0 89 0 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 12 0 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 78 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 78 0 12 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 67 0 12 0 0 0 0 0 0 0 % N
% Pro: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 12 12 0 0 0 % Q
% Arg: 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % S
% Thr: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 12 0 0 0 0 12 0 0 0 0 12 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 89 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _