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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0B All Species: 19.09
Human Site: S119 Identified Species: 30
UniProt: Q99437 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99437 NP_001034546.1 205 21406 S119 S N M A E P F S A T D P K A I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097275 205 21402 S119 S N M A E P F S A T D P K A I
Dog Lupus familis XP_539645 205 21476 S119 S N M A E P F S A T D P Q A I
Cat Felis silvestris
Mouse Mus musculus Q91V37 205 21588 S119 S N M A E P F S A T E P K A I
Rat Rattus norvegicus P63081 155 15789 L70 G I I A I Y G L V V A V L I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087741 205 21549 K119 S N M A E Q F K G T T P E A I
Zebra Danio Brachydanio rerio NP_955855 205 21470 S119 S N L A E N F S G T T P E T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23380 159 16249 V74 I A I Y G L V V A V L I A G A
Honey Bee Apis mellifera XP_392599 207 21579 T117 S G M L E K F T A E A I Q K E
Nematode Worm Caenorhab. elegans P34546 161 16391 A76 G I Y G L V V A M V L K G K V
Sea Urchin Strong. purpuratus XP_790651 209 21851 G118 S G L V K D F G T N P L K E E
Poplar Tree Populus trichocarpa
Maize Zea mays Q41773 109 11025 I24 A V I I S T G I N P K A K P Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59228 165 16624 I80 A V I I S T G I N P K A K S Y
Baker's Yeast Sacchar. cerevisiae P23968 213 22577 V127 V F S S K L T V A T A E N M Y
Red Bread Mold Neurospora crassa P31413 161 16311 D76 V V S V L I S D A L T Q D H Y
Conservation
Percent
Protein Identity: 100 N.A. 99.5 97.5 N.A. 96 29.2 N.A. N.A. N.A. 88.2 85.8 N.A. 27.3 63.7 26.8 62.2
Protein Similarity: 100 N.A. 100 99 N.A. 98 43.9 N.A. N.A. N.A. 93.6 93.1 N.A. 43.9 75.3 43.4 74.6
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 6.6 N.A. N.A. N.A. 66.6 60 N.A. 6.6 33.3 0 20
P-Site Similarity: 100 N.A. 100 100 N.A. 100 13.3 N.A. N.A. N.A. 73.3 73.3 N.A. 13.3 46.6 13.3 33.3
Percent
Protein Identity: N.A. 24.3 N.A. 28.2 49.3 29.7
Protein Similarity: N.A. 37.5 N.A. 48.2 65.2 48.2
P-Site Identity: N.A. 6.6 N.A. 6.6 13.3 6.6
P-Site Similarity: N.A. 20 N.A. 26.6 26.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 47 0 0 0 7 54 0 20 14 7 34 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 7 0 0 20 0 7 0 0 % D
% Glu: 0 0 0 0 47 0 0 0 0 7 7 7 14 7 14 % E
% Phe: 0 7 0 0 0 0 54 0 0 0 0 0 0 0 0 % F
% Gly: 14 14 0 7 7 0 20 7 14 0 0 0 7 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 7 14 27 14 7 7 0 14 0 0 0 14 0 7 40 % I
% Lys: 0 0 0 0 14 7 0 7 0 0 14 7 40 14 0 % K
% Leu: 0 0 14 7 14 14 0 7 0 7 14 7 7 0 0 % L
% Met: 0 0 40 0 0 0 0 0 7 0 0 0 0 7 0 % M
% Asn: 0 40 0 0 0 7 0 0 14 7 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 27 0 0 0 14 7 40 0 7 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 7 14 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 54 0 14 7 14 0 7 34 0 0 0 0 0 7 0 % S
% Thr: 0 0 0 0 0 14 7 7 7 47 20 0 0 7 0 % T
% Val: 14 20 0 14 0 7 14 14 7 20 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 0 7 0 0 0 0 0 0 0 0 27 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _