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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0B
All Species:
26.67
Human Site:
S184
Identified Species:
41.9
UniProt:
Q99437
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99437
NP_001034546.1
205
21406
S184
L
I
V
E
I
F
G
S
A
I
G
L
F
G
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097275
205
21402
S184
L
I
V
E
I
F
G
S
A
I
G
L
F
G
V
Dog
Lupus familis
XP_539645
205
21476
S184
L
I
V
E
I
F
G
S
A
I
G
L
F
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91V37
205
21588
S184
L
I
V
E
I
F
G
S
A
I
G
L
F
G
V
Rat
Rattus norvegicus
P63081
155
15789
L135
F
V
G
M
I
L
I
L
I
F
A
E
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087741
205
21549
S184
L
I
V
E
I
F
G
S
A
I
G
L
F
G
V
Zebra Danio
Brachydanio rerio
NP_955855
205
21470
S184
L
I
V
E
I
F
G
S
A
I
G
L
F
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23380
159
16249
L139
F
V
G
M
I
L
I
L
I
F
A
E
V
L
G
Honey Bee
Apis mellifera
XP_392599
207
21579
F182
K
I
L
I
V
E
I
F
G
S
A
I
G
L
F
Nematode Worm
Caenorhab. elegans
P34546
161
16391
L141
F
V
G
M
I
L
I
L
I
F
S
E
V
L
G
Sea Urchin
Strong. purpuratus
XP_790651
209
21851
G183
V
L
I
V
E
I
F
G
S
A
I
G
L
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41773
109
11025
A89
L
I
F
A
E
A
L
A
L
Y
G
L
I
V
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59228
165
16624
A145
L
I
F
A
E
A
L
A
L
Y
G
L
I
V
G
Baker's Yeast
Sacchar. cerevisiae
P23968
213
22577
S192
L
V
I
E
I
F
G
S
I
L
G
L
L
G
L
Red Bread Mold
Neurospora crassa
P31413
161
16311
G141
L
I
F
A
E
V
L
G
L
Y
G
L
I
V
A
Conservation
Percent
Protein Identity:
100
N.A.
99.5
97.5
N.A.
96
29.2
N.A.
N.A.
N.A.
88.2
85.8
N.A.
27.3
63.7
26.8
62.2
Protein Similarity:
100
N.A.
100
99
N.A.
98
43.9
N.A.
N.A.
N.A.
93.6
93.1
N.A.
43.9
75.3
43.4
74.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
N.A.
N.A.
100
100
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
N.A.
100
100
N.A.
13.3
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
24.3
N.A.
28.2
49.3
29.7
Protein Similarity:
N.A.
37.5
N.A.
48.2
65.2
48.2
P-Site Identity:
N.A.
26.6
N.A.
26.6
60
26.6
P-Site Similarity:
N.A.
33.3
N.A.
33.3
86.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
14
0
14
40
7
20
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
47
27
7
0
0
0
0
0
20
0
0
0
% E
% Phe:
20
0
20
0
0
47
7
7
0
20
0
0
40
7
7
% F
% Gly:
0
0
20
0
0
0
47
14
7
0
67
7
7
47
40
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
67
14
7
67
7
27
0
27
40
7
7
20
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
67
7
7
0
0
20
20
20
20
7
0
67
14
27
7
% L
% Met:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
47
7
7
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
27
40
7
7
7
0
0
0
0
0
0
20
20
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _