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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0B All Species: 21.82
Human Site: Y131 Identified Species: 34.29
UniProt: Q99437 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99437 NP_001034546.1 205 21406 Y131 K A I G H R N Y H A G Y S M F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097275 205 21402 Y131 K A I G H R N Y H A G Y S M F
Dog Lupus familis XP_539645 205 21476 Y131 Q A I G H R N Y H A G Y S M F
Cat Felis silvestris
Mouse Mus musculus Q91V37 205 21588 Y131 K A I G H R N Y H A G Y S M F
Rat Rattus norvegicus P63081 155 15789 D82 L I A N S L T D G I T L Y R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087741 205 21549 Y131 E A I G N R N Y H A G F S M F
Zebra Danio Brachydanio rerio NP_955855 205 21470 Y131 E T I G S K N Y Q A G Y S M F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23380 159 16249 S86 A G A L E E P S K Y S L Y R G
Honey Bee Apis mellifera XP_392599 207 21579 Q129 Q K E E V R D Q N W F A G Y L
Nematode Worm Caenorhab. elegans P34546 161 16391 A88 G K V T S A S A G Y D L N K G
Sea Urchin Strong. purpuratus XP_790651 209 21851 N130 K E E T V A A N Y L A G Y A I
Poplar Tree Populus trichocarpa
Maize Zea mays Q41773 109 11025 G36 K P Y Y L F D G Y A H L S S G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59228 165 16624 G92 K S Y Y L F D G Y A H L S S G
Baker's Yeast Sacchar. cerevisiae P23968 213 22577 L139 N M Y S K S N L Y T G Y S L F
Red Bread Mold Neurospora crassa P31413 161 16311 G88 D H Y A L Y T G F I Q L G A G
Conservation
Percent
Protein Identity: 100 N.A. 99.5 97.5 N.A. 96 29.2 N.A. N.A. N.A. 88.2 85.8 N.A. 27.3 63.7 26.8 62.2
Protein Similarity: 100 N.A. 100 99 N.A. 98 43.9 N.A. N.A. N.A. 93.6 93.1 N.A. 43.9 75.3 43.4 74.6
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 0 N.A. N.A. N.A. 80 66.6 N.A. 0 6.6 0 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 0 N.A. N.A. N.A. 100 80 N.A. 0 26.6 20 13.3
Percent
Protein Identity: N.A. 24.3 N.A. 28.2 49.3 29.7
Protein Similarity: N.A. 37.5 N.A. 48.2 65.2 48.2
P-Site Identity: N.A. 20 N.A. 20 33.3 0
P-Site Similarity: N.A. 33.3 N.A. 40 46.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 34 14 7 0 14 7 7 0 54 7 7 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 20 7 0 0 7 0 0 0 0 % D
% Glu: 14 7 14 7 7 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 14 0 0 7 0 7 7 0 0 47 % F
% Gly: 7 7 0 40 0 0 0 20 14 0 47 7 14 0 34 % G
% His: 0 7 0 0 27 0 0 0 34 0 14 0 0 0 0 % H
% Ile: 0 7 40 0 0 0 0 0 0 14 0 0 0 0 7 % I
% Lys: 40 14 0 0 7 7 0 0 7 0 0 0 0 7 0 % K
% Leu: 7 0 0 7 20 7 0 7 0 7 0 40 0 7 7 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 40 0 % M
% Asn: 7 0 0 7 7 0 47 7 7 0 0 0 7 0 0 % N
% Pro: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 14 0 0 0 0 0 0 7 7 0 7 0 0 0 0 % Q
% Arg: 0 0 0 0 0 40 0 0 0 0 0 0 0 14 0 % R
% Ser: 0 7 0 7 20 7 7 7 0 0 7 0 60 14 7 % S
% Thr: 0 7 0 14 0 0 14 0 0 7 7 0 0 0 0 % T
% Val: 0 0 7 0 14 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 27 14 0 7 0 40 27 14 0 40 20 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _