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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC62 All Species: 17.27
Human Site: S150 Identified Species: 27.14
UniProt: Q99442 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99442 NP_003253.1 399 45862 S150 K D G E K E E S K K E E T P G
Chimpanzee Pan troglodytes XP_001162758 361 41344 T126 G T P K K K E T K K K F K L E
Rhesus Macaque Macaca mulatta XP_001090325 399 45895 P150 K D G E K E E P K K E E T P G
Dog Lupus familis XP_851757 473 53390 P224 K D G E K E E P K K E E T P G
Cat Felis silvestris
Mouse Mus musculus Q8BU14 398 45562 S150 K D G E K E D S K K E E T P G
Rat Rattus norvegicus NP_001029301 605 67912 S357 K D G E K E D S K K E E T P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513885 329 37691 K94 K E T K K K F K L E P H E D Q
Chicken Gallus gallus Q5F3A1 398 45947 C150 K D G E K E E C K K D E T P G
Frog Xenopus laevis NP_001086825 400 45931 V150 K E T E K E E V K K D E T P G
Zebra Danio Brachydanio rerio NP_001020701 394 45408 T148 K D S E A A D T K K E K N D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477008 415 47060 N155 G D G G A S G N E K E K E K K
Honey Bee Apis mellifera XP_394392 364 42609 S129 E I K K E K K S E K E K E E P
Nematode Worm Caenorhab. elegans NP_495908 364 41710 A129 V E K R N K K A K E E E T A T
Sea Urchin Strong. purpuratus XP_001181087 393 44821 A148 G A K D T K D A G K E E T P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21825 274 31328 F39 L K Q R Q G L F Q A K Q T D F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 99.2 82.4 N.A. 93.7 61.8 N.A. 72.1 91.7 83 74.6 N.A. 35.9 38.5 36.5 40.8
Protein Similarity: 100 90.4 99.5 83.9 N.A. 97.9 64.3 N.A. 77.1 95.4 90.7 83.4 N.A. 55.6 55.3 57.1 56.3
P-Site Identity: 100 26.6 93.3 93.3 N.A. 93.3 93.3 N.A. 13.3 86.6 73.3 40 N.A. 26.6 20 26.6 33.3
P-Site Similarity: 100 53.3 93.3 93.3 N.A. 100 100 N.A. 40 93.3 86.6 60 N.A. 46.6 66.6 60 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 14 7 0 14 0 7 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 54 0 7 0 0 27 0 0 0 14 0 0 20 7 % D
% Glu: 7 20 0 54 7 47 40 0 14 14 67 60 20 7 7 % E
% Phe: 0 0 0 0 0 0 7 7 0 0 0 7 0 0 7 % F
% Gly: 20 0 47 7 0 7 7 0 7 0 0 0 0 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 60 7 20 20 60 34 14 7 67 80 14 20 7 7 7 % K
% Leu: 7 0 0 0 0 0 7 0 7 0 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 7 0 0 0 0 7 0 0 % N
% Pro: 0 0 7 0 0 0 0 14 0 0 7 0 0 54 14 % P
% Gln: 0 0 7 0 7 0 0 0 7 0 0 7 0 0 7 % Q
% Arg: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 0 0 7 0 27 0 0 0 0 0 0 0 % S
% Thr: 0 7 14 0 7 0 0 14 0 0 0 0 67 0 7 % T
% Val: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _