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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC62 All Species: 26.06
Human Site: S307 Identified Species: 40.95
UniProt: Q99442 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99442 NP_003253.1 399 45862 S307 E T K K Q Q K S D S E E K S D
Chimpanzee Pan troglodytes XP_001162758 361 41344 E273 Q Q K S D S E E K S D S E K K
Rhesus Macaque Macaca mulatta XP_001090325 399 45895 S307 E T K K Q Q K S D S E E K S D
Dog Lupus familis XP_851757 473 53390 S381 E T K K Q Q K S D S E E K S D
Cat Felis silvestris
Mouse Mus musculus Q8BU14 398 45562 S307 E T K K Q Q K S D S E E K S D
Rat Rattus norvegicus NP_001029301 605 67912 S514 E A K K Q H K S D S E E K S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513885 329 37691 E241 S E E K S D S E K K E E D D G
Chicken Gallus gallus Q5F3A1 398 45947 Y307 E S K K Q Q K Y D S E E K S D
Frog Xenopus laevis NP_001086825 400 45931 S307 E E K K P L K S D S E D K S D
Zebra Danio Brachydanio rerio NP_001020701 394 45408 K305 S S D K P D S K S A D S S K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477008 415 47060 K308 K S K S K D K K K E K E S D A
Honey Bee Apis mellifera XP_394392 364 42609 Q276 A S F W P P Y Q Y E Y Y G S T
Nematode Worm Caenorhab. elegans NP_495908 364 41710 Y276 S F Q P W Y T Y E Y V G D E K
Sea Urchin Strong. purpuratus XP_001181087 393 44821 G303 E D S N D E R G S E A A E V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21825 274 31328 G186 Y V S L G A F G I L A G F F A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 99.2 82.4 N.A. 93.7 61.8 N.A. 72.1 91.7 83 74.6 N.A. 35.9 38.5 36.5 40.8
Protein Similarity: 100 90.4 99.5 83.9 N.A. 97.9 64.3 N.A. 77.1 95.4 90.7 83.4 N.A. 55.6 55.3 57.1 56.3
P-Site Identity: 100 13.3 100 100 N.A. 100 86.6 N.A. 20 86.6 73.3 6.6 N.A. 20 6.6 0 6.6
P-Site Similarity: 100 40 100 100 N.A. 100 86.6 N.A. 26.6 93.3 80 26.6 N.A. 46.6 13.3 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 7 0 0 0 7 14 7 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 14 20 0 0 47 0 14 7 14 14 47 % D
% Glu: 54 14 7 0 0 7 7 14 7 20 54 54 14 7 7 % E
% Phe: 0 7 7 0 0 0 7 0 0 0 0 0 7 7 0 % F
% Gly: 0 0 0 0 7 0 0 14 0 0 0 14 7 0 7 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 7 0 60 60 7 0 54 14 20 7 7 0 47 14 14 % K
% Leu: 0 0 0 7 0 7 0 0 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 20 7 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 7 7 0 40 34 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 20 27 14 14 7 7 14 40 14 54 0 14 14 54 0 % S
% Thr: 0 27 0 0 0 0 7 0 0 0 0 0 0 0 7 % T
% Val: 0 7 0 0 0 0 0 0 0 0 7 0 0 7 0 % V
% Trp: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 7 14 7 7 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _