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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC62 All Species: 28.18
Human Site: S315 Identified Species: 44.29
UniProt: Q99442 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99442 NP_003253.1 399 45862 S315 D S E E K S D S E K K E D E E
Chimpanzee Pan troglodytes XP_001162758 361 41344 E281 K S D S E K K E D E E G K V G
Rhesus Macaque Macaca mulatta XP_001090325 399 45895 S315 D S E E K S D S E K K E D E E
Dog Lupus familis XP_851757 473 53390 S389 D S E E K S D S E K K E E E E
Cat Felis silvestris
Mouse Mus musculus Q8BU14 398 45562 S315 D S E E K S D S E K K E D E E
Rat Rattus norvegicus NP_001029301 605 67912 S522 D S E E K S D S E K K E D E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513885 329 37691 K249 K K E E D D G K A G P L G R T
Chicken Gallus gallus Q5F3A1 398 45947 S315 D S E E K S D S E K K E E E D
Frog Xenopus laevis NP_001086825 400 45931 S315 D S E D K S D S E K K E E E D
Zebra Danio Brachydanio rerio NP_001020701 394 45408 Q313 S A D S S K A Q K S D S E D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477008 415 47060 E316 K E K E S D A E D T A V D A D
Honey Bee Apis mellifera XP_394392 364 42609 S284 Y E Y Y G S T S E S D R K V S
Nematode Worm Caenorhab. elegans NP_495908 364 41710 K284 E Y V G D E K K E A K K D K K
Sea Urchin Strong. purpuratus XP_001181087 393 44821 D311 S E A A E V E D Q P K Q E I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21825 274 31328 V194 I L A G F F A V A I L R L I L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 99.2 82.4 N.A. 93.7 61.8 N.A. 72.1 91.7 83 74.6 N.A. 35.9 38.5 36.5 40.8
Protein Similarity: 100 90.4 99.5 83.9 N.A. 97.9 64.3 N.A. 77.1 95.4 90.7 83.4 N.A. 55.6 55.3 57.1 56.3
P-Site Identity: 100 6.6 100 93.3 N.A. 100 100 N.A. 13.3 86.6 80 0 N.A. 13.3 20 20 6.6
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 13.3 100 100 40 N.A. 33.3 20 46.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 14 7 0 0 20 0 14 7 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 47 0 14 7 14 14 47 7 14 0 14 0 40 7 20 % D
% Glu: 7 20 54 54 14 7 7 14 60 7 7 47 34 47 34 % E
% Phe: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 14 7 0 7 0 0 7 0 7 7 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 7 0 0 0 14 0 % I
% Lys: 20 7 7 0 47 14 14 14 7 47 60 7 14 7 14 % K
% Leu: 0 7 0 0 0 0 0 0 0 0 7 7 7 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 7 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 14 0 7 0 % R
% Ser: 14 54 0 14 14 54 0 54 0 14 0 7 0 0 14 % S
% Thr: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 7 % T
% Val: 0 0 7 0 0 7 0 7 0 0 0 7 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 7 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _