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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
25.76
Human Site:
S335
Identified Species:
40.48
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
S335
G
N
H
G
T
E
G
S
G
G
E
R
H
S
D
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
G299
H
G
T
E
G
S
G
G
E
R
H
S
D
T
D
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
S335
G
N
H
G
T
E
G
S
G
G
E
R
H
S
D
Dog
Lupus familis
XP_851757
473
53390
S409
G
N
H
G
T
E
G
S
G
G
E
R
H
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
S335
A
D
H
G
P
E
G
S
G
G
E
R
H
S
D
Rat
Rattus norvegicus
NP_001029301
605
67912
S542
G
D
H
G
P
E
G
S
G
G
E
R
H
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
S267
G
S
G
G
E
R
H
S
D
T
D
S
D
R
R
Chicken
Gallus gallus
Q5F3A1
398
45947
S336
R
N
S
G
T
E
G
S
G
G
E
R
H
S
D
Frog
Xenopus laevis
NP_001086825
400
45931
S336
E
G
S
G
T
E
G
S
G
A
E
R
Q
S
D
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
D331
E
K
K
E
D
E
E
D
E
D
D
N
K
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
E340
E
V
S
T
L
E
P
E
K
I
E
L
I
K
E
Honey Bee
Apis mellifera
XP_394392
364
42609
D302
K
K
K
E
K
D
S
D
T
E
E
T
P
T
Q
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
D302
S
K
K
E
K
D
S
D
A
E
E
E
E
Q
D
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
I331
V
E
N
I
P
E
N
I
G
D
T
E
E
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
V212
S
L
I
V
Y
K
D
V
G
G
F
W
I
F
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
13.3
100
100
N.A.
80
86.6
N.A.
20
86.6
66.6
6.6
N.A.
13.3
6.6
13.3
13.3
P-Site Similarity:
100
20
100
100
N.A.
86.6
93.3
N.A.
33.3
86.6
66.6
13.3
N.A.
20
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
14
0
0
7
14
7
20
7
14
14
0
14
7
60
% D
% Glu:
20
7
0
27
7
67
7
7
14
14
67
14
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% F
% Gly:
34
14
7
54
7
0
54
7
60
47
0
0
0
0
0
% G
% His:
7
0
34
0
0
0
7
0
0
0
7
0
40
0
0
% H
% Ile:
0
0
7
7
0
0
0
7
0
7
0
0
14
0
0
% I
% Lys:
7
20
20
0
14
7
0
0
7
0
0
0
7
7
0
% K
% Leu:
0
7
0
0
7
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
27
7
0
0
0
7
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
20
0
7
0
0
0
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% Q
% Arg:
7
0
0
0
0
7
0
0
0
7
0
47
0
14
7
% R
% Ser:
14
7
20
0
0
7
14
54
0
0
0
14
0
47
0
% S
% Thr:
0
0
7
7
34
0
0
0
7
7
7
7
0
14
0
% T
% Val:
7
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _