KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
28.48
Human Site:
S345
Identified Species:
44.76
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
S345
E
R
H
S
D
T
D
S
D
R
R
E
D
D
R
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
R309
H
S
D
T
D
S
D
R
R
E
D
D
R
S
Q
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
S345
E
R
H
S
D
T
D
S
D
R
R
E
D
D
R
Dog
Lupus familis
XP_851757
473
53390
S419
E
R
H
S
D
T
D
S
D
R
R
E
D
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
S345
E
R
H
S
D
T
D
S
D
R
R
E
D
D
R
Rat
Rattus norvegicus
NP_001029301
605
67912
S552
E
R
H
S
D
T
D
S
D
R
R
E
D
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
D277
D
S
D
R
R
E
D
D
R
S
Q
H
S
S
G
Chicken
Gallus gallus
Q5F3A1
398
45947
S346
E
R
H
S
D
T
D
S
D
R
R
E
D
D
R
Frog
Xenopus laevis
NP_001086825
400
45931
S346
E
R
Q
S
D
T
D
S
D
R
R
E
D
E
G
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
G341
D
N
K
D
M
E
E
G
G
H
Q
T
D
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
T350
E
L
I
K
E
H
D
T
D
M
E
I
R
K
R
Honey Bee
Apis mellifera
XP_394392
364
42609
E312
E
T
P
T
Q
L
E
E
K
P
S
I
K
E
L
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
A312
E
E
E
Q
D
H
I
A
A
E
Q
E
Q
K
E
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
Q341
T
E
E
R
C
S
D
Q
A
V
T
P
P
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
F222
F
W
I
F
P
N
L
F
E
D
C
G
V
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
100
80
6.6
N.A.
26.6
6.6
20
6.6
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
20
100
86.6
26.6
N.A.
40
26.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
14
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
14
0
14
7
60
0
74
7
54
7
7
7
54
40
7
% D
% Glu:
67
14
14
0
7
14
14
7
7
14
7
54
0
20
14
% E
% Phe:
7
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
0
7
0
0
14
% G
% His:
7
0
40
0
0
14
0
0
0
7
0
7
0
0
0
% H
% Ile:
0
0
14
0
0
0
7
0
0
0
0
14
0
0
0
% I
% Lys:
0
0
7
7
0
0
0
0
7
0
0
0
7
14
0
% K
% Leu:
0
7
0
0
0
7
7
0
0
0
0
0
0
7
7
% L
% Met:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
7
0
7
0
0
0
0
7
0
7
7
0
0
% P
% Gln:
0
0
7
7
7
0
0
7
0
0
20
0
7
0
7
% Q
% Arg:
0
47
0
14
7
0
0
7
14
47
47
0
14
0
47
% R
% Ser:
0
14
0
47
0
14
0
47
0
7
7
0
7
14
0
% S
% Thr:
7
7
0
14
0
47
0
7
0
0
7
7
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _