KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
27.27
Human Site:
T135
Identified Species:
42.86
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
T135
E
N
I
K
D
E
K
T
K
K
E
K
E
K
K
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
E111
K
K
D
G
E
K
E
E
S
K
K
E
E
T
P
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
T135
E
N
I
K
D
E
K
T
K
K
E
K
E
K
K
Dog
Lupus familis
XP_851757
473
53390
T209
E
N
L
K
D
E
K
T
K
K
E
K
E
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
T135
E
S
V
K
E
E
K
T
K
K
E
K
E
K
K
Rat
Rattus norvegicus
NP_001029301
605
67912
T342
E
S
I
K
E
E
K
T
K
K
E
K
E
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
E79
K
E
E
S
K
K
E
E
T
P
G
T
P
K
K
Chicken
Gallus gallus
Q5F3A1
398
45947
T135
E
S
S
K
D
E
K
T
K
K
E
K
E
K
K
Frog
Xenopus laevis
NP_001086825
400
45931
E135
K
K
D
P
P
K
E
E
K
S
K
K
E
K
K
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
S133
S
K
E
E
E
K
K
S
K
K
D
K
D
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
D140
K
D
E
K
K
D
T
D
P
E
G
D
N
G
Q
Honey Bee
Apis mellifera
XP_394392
364
42609
R114
E
E
E
L
Y
K
I
R
G
I
K
K
K
V
K
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
V114
G
N
D
S
S
A
E
V
T
K
S
P
K
G
V
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
E133
T
E
K
G
D
D
K
E
K
E
E
T
K
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
T24
G
S
A
T
A
I
A
T
L
L
R
N
H
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
13.3
100
93.3
N.A.
80
86.6
N.A.
13.3
86.6
33.3
40
N.A.
6.6
20
13.3
26.6
P-Site Similarity:
100
53.3
100
100
N.A.
100
100
N.A.
33.3
93.3
60
80
N.A.
40
40
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
20
0
34
14
0
7
0
0
7
7
7
0
7
% D
% Glu:
47
20
27
7
27
40
27
27
0
14
47
7
54
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
14
0
0
0
0
7
0
14
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
20
0
0
7
7
0
0
7
0
0
0
0
0
% I
% Lys:
27
20
7
47
14
34
54
0
60
60
20
60
20
67
67
% K
% Leu:
0
0
7
7
0
0
0
0
7
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
27
0
0
0
0
0
0
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
7
7
0
0
0
7
7
0
7
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% R
% Ser:
7
27
7
14
7
0
0
7
7
7
7
0
0
0
0
% S
% Thr:
7
0
0
7
0
0
7
47
14
0
0
14
0
7
0
% T
% Val:
0
0
7
0
0
0
0
7
0
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _