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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC62 All Species: 20.91
Human Site: T301 Identified Species: 32.86
UniProt: Q99442 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99442 NP_003253.1 399 45862 T301 K K D E K S E T K K Q Q K S D
Chimpanzee Pan troglodytes XP_001162758 361 41344 Q267 K S E T K K Q Q K S D S E E K
Rhesus Macaque Macaca mulatta XP_001090325 399 45895 T301 K K D E K S E T K K Q Q K S D
Dog Lupus familis XP_851757 473 53390 T375 K K D E K S E T K K Q Q K S D
Cat Felis silvestris
Mouse Mus musculus Q8BU14 398 45562 T301 K K D E K S E T K K Q Q K S D
Rat Rattus norvegicus NP_001029301 605 67912 A508 K K D E K S E A K K Q H K S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513885 329 37691 E235 K H Q K S D S E E K S D S E K
Chicken Gallus gallus Q5F3A1 398 45947 S301 K K E E K S E S K K Q Q K Y D
Frog Xenopus laevis NP_001086825 400 45931 E301 N K E E K S E E K K P L K S D
Zebra Danio Brachydanio rerio NP_001020701 394 45408 S299 R S G S K K S S D K P D S K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477008 415 47060 S302 S A K T D K K S K S K D K K K
Honey Bee Apis mellifera XP_394392 364 42609 S270 A D V G F F A S F W P P Y Q Y
Nematode Worm Caenorhab. elegans NP_495908 364 41710 F270 D C G V L E S F Q P W Y T Y E
Sea Urchin Strong. purpuratus XP_001181087 393 44821 D297 K T E K S K E D S N D E R G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21825 274 31328 V180 M R R G S Y Y V S L G A F G I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 99.2 82.4 N.A. 93.7 61.8 N.A. 72.1 91.7 83 74.6 N.A. 35.9 38.5 36.5 40.8
Protein Similarity: 100 90.4 99.5 83.9 N.A. 97.9 64.3 N.A. 77.1 95.4 90.7 83.4 N.A. 55.6 55.3 57.1 56.3
P-Site Identity: 100 20 100 100 N.A. 100 86.6 N.A. 13.3 80 66.6 13.3 N.A. 13.3 0 0 13.3
P-Site Similarity: 100 40 100 100 N.A. 100 86.6 N.A. 26.6 93.3 73.3 26.6 N.A. 33.3 6.6 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 0 7 7 0 0 0 7 0 0 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 34 0 7 7 0 7 7 0 14 20 0 0 47 % D
% Glu: 0 0 27 47 0 7 54 14 7 0 0 7 7 14 7 % E
% Phe: 0 0 0 0 7 7 0 7 7 0 0 0 7 0 0 % F
% Gly: 0 0 14 14 0 0 0 0 0 0 7 0 0 14 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 60 47 7 14 60 27 7 0 60 60 7 0 54 14 20 % K
% Leu: 0 0 0 0 7 0 0 0 0 7 0 7 0 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 20 7 0 0 0 % P
% Gln: 0 0 7 0 0 0 7 7 7 0 40 34 0 7 0 % Q
% Arg: 7 7 7 0 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 7 14 0 7 20 47 20 27 14 14 7 7 14 40 14 % S
% Thr: 0 7 0 14 0 0 0 27 0 0 0 0 7 0 0 % T
% Val: 0 0 7 7 0 0 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 7 0 0 0 0 7 7 14 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _