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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
18.18
Human Site:
T391
Identified Species:
28.57
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
T391
E
E
E
N
D
G
E
T
P
K
S
S
H
E
K
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
P354
E
E
N
D
G
E
T
P
K
S
S
H
E
K
S
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
T391
E
E
E
N
D
G
E
T
P
K
S
S
H
E
K
Dog
Lupus familis
XP_851757
473
53390
T465
E
E
D
N
D
G
E
T
T
K
S
S
H
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
V390
D
D
D
K
D
G
E
V
P
K
S
A
H
E
K
Rat
Rattus norvegicus
NP_001029301
605
67912
M597
D
D
D
K
D
G
E
M
P
K
S
A
Q
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
T322
E
E
N
N
E
E
T
T
R
P
S
Q
E
K
S
Chicken
Gallus gallus
Q5F3A1
398
45947
S391
D
E
D
E
D
T
E
S
R
P
S
H
E
K
S
Frog
Xenopus laevis
NP_001086825
400
45931
E392
E
E
E
E
G
T
A
E
S
R
P
L
C
E
E
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
T387
E
E
E
E
Q
S
Q
T
K
P
L
T
V
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
S396
N
S
G
S
D
S
E
S
S
S
K
D
Y
E
I
Honey Bee
Apis mellifera
XP_394392
364
42609
T357
S
E
S
E
K
S
N
T
G
R
D
F
V
M
V
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
R357
S
P
S
D
D
A
P
R
K
R
R
P
A
K
V
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
R386
A
H
K
M
Y
L
R
R
M
A
P
K
F
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
I267
E
S
N
K
K
K
A
I
N
E
K
A
E
Q
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
20
100
86.6
N.A.
60
53.3
N.A.
33.3
26.6
26.6
26.6
N.A.
20
13.3
6.6
0
P-Site Similarity:
100
33.3
100
93.3
N.A.
86.6
80
N.A.
46.6
53.3
40
46.6
N.A.
40
20
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
14
0
0
7
0
20
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
20
14
27
14
54
0
0
0
0
0
7
7
0
0
0
% D
% Glu:
54
60
27
27
7
14
47
7
0
7
0
0
27
47
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
7
% F
% Gly:
0
0
7
0
14
34
0
0
7
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
14
27
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% I
% Lys:
0
0
7
20
14
7
0
0
20
34
14
7
0
27
34
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
7
7
0
0
0
% L
% Met:
0
0
0
7
0
0
0
7
7
0
0
0
0
7
0
% M
% Asn:
7
0
20
27
0
0
7
0
7
0
0
0
0
0
7
% N
% Pro:
0
7
0
0
0
0
7
7
27
20
14
7
0
0
0
% P
% Gln:
0
0
0
0
7
0
7
0
0
0
0
7
7
14
0
% Q
% Arg:
0
0
0
0
0
0
7
14
14
20
7
0
0
0
0
% R
% Ser:
14
14
14
7
0
20
0
14
14
14
54
20
0
0
20
% S
% Thr:
0
0
0
0
0
14
14
40
7
0
0
7
0
0
7
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
0
14
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _