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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC62 All Species: 18.18
Human Site: Y102 Identified Species: 28.57
UniProt: Q99442 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99442 NP_003253.1 399 45862 Y102 L K V M K M K Y D K D I K K E
Chimpanzee Pan troglodytes XP_001162758 361 41344 E78 E K D K G K A E S G K E E D K
Rhesus Macaque Macaca mulatta XP_001090325 399 45895 Y102 L K V M K M K Y D K D I K K E
Dog Lupus familis XP_851757 473 53390 Y176 L K V M K M K Y D K D I K K E
Cat Felis silvestris
Mouse Mus musculus Q8BU14 398 45562 Y102 L K V M K M K Y D K D V K K E
Rat Rattus norvegicus NP_001029301 605 67912 Y309 L K V M K M K Y D K D I K K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513885 329 37691 R46 E S G K E E E R R S K K E S V
Chicken Gallus gallus Q5F3A1 398 45947 P102 L K V M K M K P D K D T K K E
Frog Xenopus laevis NP_001086825 400 45931 P102 L K V M K T K P E K E V K K E
Zebra Danio Brachydanio rerio NP_001020701 394 45408 K100 R A L K V M K K K P E K D V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477008 415 47060 E107 K K V P V T L E E I R G K S G
Honey Bee Apis mellifera XP_394392 364 42609 R81 S K T K F E K R K Q V T E F L
Nematode Worm Caenorhab. elegans NP_495908 364 41710 I81 R D D C F H Y I C E L N S K Q
Sea Urchin Strong. purpuratus XP_001181087 393 44821 I100 L F Y R A L K I V K K G K K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21825 274 31328
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 99.2 82.4 N.A. 93.7 61.8 N.A. 72.1 91.7 83 74.6 N.A. 35.9 38.5 36.5 40.8
Protein Similarity: 100 90.4 99.5 83.9 N.A. 97.9 64.3 N.A. 77.1 95.4 90.7 83.4 N.A. 55.6 55.3 57.1 56.3
P-Site Identity: 100 6.6 100 100 N.A. 93.3 100 N.A. 0 86.6 66.6 13.3 N.A. 20 13.3 6.6 40
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 20 86.6 86.6 33.3 N.A. 26.6 26.6 20 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 7 14 0 0 0 0 0 40 0 40 0 7 7 0 % D
% Glu: 14 0 0 0 7 14 7 14 14 7 14 7 20 0 54 % E
% Phe: 0 7 0 0 14 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 7 0 7 0 0 0 0 7 0 14 0 0 7 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 14 0 7 0 27 0 0 0 % I
% Lys: 7 67 0 27 47 7 67 7 14 54 20 14 60 60 14 % K
% Leu: 54 0 7 0 0 7 7 0 0 0 7 0 0 0 7 % L
% Met: 0 0 0 47 0 47 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 7 0 0 0 14 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % Q
% Arg: 14 0 0 7 0 0 0 14 7 0 7 0 0 0 0 % R
% Ser: 7 7 0 0 0 0 0 0 7 7 0 0 7 14 0 % S
% Thr: 0 0 7 0 0 14 0 0 0 0 0 14 0 0 0 % T
% Val: 0 0 54 0 14 0 0 0 7 0 7 14 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _