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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
38.18
Human Site:
Y189
Identified Species:
60
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
Y189
N
E
V
Y
V
W
I
Y
D
P
V
H
F
K
T
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
F159
D
P
V
H
F
K
T
F
V
M
G
L
I
L
V
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
Y189
N
E
V
Y
V
W
I
Y
D
P
V
H
F
K
T
Dog
Lupus familis
XP_851757
473
53390
Y263
N
E
V
F
V
W
I
Y
D
P
V
H
F
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
Y189
N
E
V
F
V
W
I
Y
D
P
V
H
I
K
T
Rat
Rattus norvegicus
NP_001029301
605
67912
Y396
N
E
V
F
V
W
I
Y
D
P
V
H
I
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
I127
K
T
F
A
M
G
L
I
L
V
I
A
V
I
A
Chicken
Gallus gallus
Q5F3A1
398
45947
Y189
N
E
V
Y
V
W
I
Y
D
P
V
H
F
K
T
Frog
Xenopus laevis
NP_001086825
400
45931
Y189
N
E
V
Y
V
W
I
Y
D
P
V
H
F
K
T
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
Y191
N
E
V
Y
F
W
I
Y
D
P
V
H
F
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
Y190
S
E
A
Y
V
W
I
Y
D
P
I
P
L
H
Y
Honey Bee
Apis mellifera
XP_394392
364
42609
R162
K
K
K
K
P
K
V
R
L
E
M
H
M
E
Q
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
L162
K
K
K
K
K
V
K
L
L
V
H
E
V
Q
A
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
Y185
N
D
A
F
V
W
V
Y
D
P
I
R
P
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
Y72
S
A
R
Q
P
E
I
Y
P
T
I
P
S
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
86.6
N.A.
0
100
100
93.3
N.A.
53.3
6.6
0
40
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
20
100
100
93.3
N.A.
66.6
33.3
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
7
0
0
0
0
0
0
0
7
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
0
0
67
0
0
0
0
0
0
% D
% Glu:
0
60
0
0
0
7
0
0
0
7
0
7
0
7
0
% E
% Phe:
0
0
7
27
14
0
0
7
0
0
0
0
40
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
7
60
0
7
0
% H
% Ile:
0
0
0
0
0
0
67
7
0
0
27
0
20
7
0
% I
% Lys:
20
14
14
14
7
14
7
0
0
0
0
0
0
54
7
% K
% Leu:
0
0
0
0
0
0
7
7
20
0
0
7
7
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
7
7
0
7
7
0
% M
% Asn:
60
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% N
% Pro:
0
7
0
0
14
0
0
0
7
67
0
14
7
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
7
% Q
% Arg:
0
0
7
0
0
0
0
7
0
0
0
7
0
0
0
% R
% Ser:
14
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% S
% Thr:
0
7
0
0
0
0
7
0
0
7
0
0
0
0
54
% T
% Val:
0
0
60
0
60
7
14
0
7
14
54
0
14
0
7
% V
% Trp:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
0
0
0
74
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _