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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
31.82
Human Site:
Y27
Identified Species:
50
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
Y27
E
E
K
A
V
A
K
Y
L
R
F
N
C
P
T
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
F9
M
G
H
R
V
D
Y
F
I
A
S
K
A
V
D
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
Y27
E
E
K
A
V
A
K
Y
L
R
F
N
C
P
T
Dog
Lupus familis
XP_851757
473
53390
Y101
E
E
K
A
V
A
K
Y
L
R
F
N
C
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
Y27
E
E
K
A
V
A
K
Y
L
R
F
N
C
P
T
Rat
Rattus norvegicus
NP_001029301
605
67912
Y234
E
E
K
A
V
A
K
Y
L
R
F
N
C
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
Chicken
Gallus gallus
Q5F3A1
398
45947
Y27
E
E
K
A
V
A
K
Y
L
R
F
N
C
P
T
Frog
Xenopus laevis
NP_001086825
400
45931
Y27
D
E
K
A
I
A
K
Y
L
R
F
N
C
P
S
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
Y27
E
E
K
A
V
A
K
Y
L
R
F
N
C
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
W35
D
E
K
N
V
A
K
W
L
K
K
N
V
K
T
Honey Bee
Apis mellifera
XP_394392
364
42609
D12
R
K
S
R
K
R
K
D
Q
E
T
S
N
V
D
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
E12
N
Q
K
G
V
S
T
E
D
A
V
K
M
T
K
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
H30
E
E
T
A
V
A
R
H
L
R
F
N
L
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
0
100
80
100
N.A.
53.3
6.6
13.3
66.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
73.3
20
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
60
0
67
0
0
0
14
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% C
% Asp:
14
0
0
0
0
7
0
7
7
0
0
0
0
0
14
% D
% Glu:
54
67
0
0
0
0
0
7
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
60
0
0
0
0
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
7
% I
% Lys:
0
7
67
0
7
0
67
0
0
7
7
14
0
7
7
% K
% Leu:
0
0
0
0
0
0
0
0
67
0
0
0
7
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
0
7
0
0
0
0
0
0
0
67
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% P
% Gln:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
7
0
0
14
0
7
7
0
0
60
0
0
0
0
0
% R
% Ser:
0
0
7
0
0
7
0
0
0
0
7
7
0
0
7
% S
% Thr:
0
0
7
0
0
0
7
0
0
0
7
0
0
7
54
% T
% Val:
0
0
0
0
74
0
0
0
0
0
7
0
7
14
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _