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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
30.61
Human Site:
Y286
Identified Species:
48.1
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
Y286
R
P
L
Y
T
H
E
Y
K
G
P
K
A
D
L
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
K252
T
H
E
Y
K
G
P
K
A
D
L
K
K
D
E
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
Y286
R
P
L
Y
T
H
E
Y
K
G
P
K
A
D
L
Dog
Lupus familis
XP_851757
473
53390
Y360
R
P
L
Y
T
H
E
Y
K
G
P
K
A
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
Y286
R
P
L
Y
T
H
E
Y
K
G
P
K
A
D
L
Rat
Rattus norvegicus
NP_001029301
605
67912
Y493
R
P
L
Y
T
H
E
Y
K
G
P
K
A
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
K220
G
P
K
A
D
L
K
K
E
E
K
A
E
S
K
Chicken
Gallus gallus
Q5F3A1
398
45947
Y286
R
P
L
Y
T
H
E
Y
K
G
P
K
A
D
L
Frog
Xenopus laevis
NP_001086825
400
45931
Y286
R
P
V
Y
T
H
E
Y
K
G
P
K
P
D
Q
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
Y284
I
D
S
F
R
P
L
Y
T
H
E
Y
K
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
Y287
W
P
L
Y
E
S
N
Y
N
S
D
P
N
N
S
Honey Bee
Apis mellifera
XP_394392
364
42609
L255
P
T
L
G
R
C
H
L
W
L
L
P
N
L
T
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
W255
T
F
G
K
H
K
L
W
V
L
P
N
L
T
E
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
Y282
M
P
F
Y
E
V
D
Y
M
T
K
K
E
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
C165
S
I
I
L
A
L
V
C
Y
P
L
W
P
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
6.6
100
80
6.6
N.A.
26.6
6.6
6.6
33.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
20
100
86.6
13.3
N.A.
33.3
6.6
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
0
7
0
0
7
40
0
0
% A
% Cys:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
0
7
0
0
7
7
0
0
60
7
% D
% Glu:
0
0
7
0
14
0
47
0
7
7
7
0
14
0
14
% E
% Phe:
0
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
7
0
7
0
0
0
47
0
0
0
7
0
% G
% His:
0
7
0
0
7
47
7
0
0
7
0
0
0
0
0
% H
% Ile:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
7
7
7
7
14
47
0
14
60
14
0
7
% K
% Leu:
0
0
54
7
0
14
14
7
0
14
20
0
7
7
40
% L
% Met:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
7
0
0
7
14
7
0
% N
% Pro:
7
67
0
0
0
7
7
0
0
7
54
14
14
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
47
0
0
0
14
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
7
0
7
0
0
7
0
0
0
7
0
0
0
7
14
% S
% Thr:
14
7
0
0
47
0
0
0
7
7
0
0
0
7
7
% T
% Val:
0
0
7
0
0
7
7
0
7
0
0
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% W
% Tyr:
0
0
0
67
0
0
0
67
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _