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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC62
All Species:
30.3
Human Site:
Y81
Identified Species:
47.62
UniProt:
Q99442
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99442
NP_003253.1
399
45862
Y81
T
R
E
S
V
V
D
Y
C
N
R
L
L
K
K
Chimpanzee
Pan troglodytes
XP_001162758
361
41344
K63
A
L
K
V
M
K
M
K
Y
D
K
D
I
K
K
Rhesus Macaque
Macaca mulatta
XP_001090325
399
45895
Y81
T
R
E
S
V
V
D
Y
C
N
R
L
L
K
K
Dog
Lupus familis
XP_851757
473
53390
Y155
T
R
E
S
V
V
D
Y
C
N
R
L
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU14
398
45562
Y81
T
R
E
S
V
V
D
Y
C
N
R
L
L
K
K
Rat
Rattus norvegicus
NP_001029301
605
67912
Y288
T
R
E
S
V
V
D
Y
C
N
R
L
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513885
329
37691
K31
K
P
D
K
D
T
K
K
E
K
E
K
S
K
A
Chicken
Gallus gallus
Q5F3A1
398
45947
Y81
T
R
E
S
V
V
D
Y
C
N
R
L
L
K
K
Frog
Xenopus laevis
NP_001086825
400
45931
F81
N
R
E
S
V
V
E
F
C
N
R
L
L
K
K
Zebra Danio
Brachydanio rerio
NP_001020701
394
45408
Y81
T
R
E
S
V
V
D
Y
C
N
R
L
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477008
415
47060
V89
Q
V
I
E
F
L
D
V
M
L
E
H
K
F
F
Honey Bee
Apis mellifera
XP_394392
364
42609
A66
T
G
S
R
A
V
D
A
L
L
E
N
S
P
W
Nematode Worm
Caenorhab. elegans
NP_495908
364
41710
K66
S
K
Y
G
N
K
A
K
K
D
A
M
F
K
T
Sea Urchin
Strong. purpuratus
XP_001181087
393
44821
Y84
D
R
E
S
V
A
N
Y
L
D
G
L
L
W
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21825
274
31328
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99.2
82.4
N.A.
93.7
61.8
N.A.
72.1
91.7
83
74.6
N.A.
35.9
38.5
36.5
40.8
Protein Similarity:
100
90.4
99.5
83.9
N.A.
97.9
64.3
N.A.
77.1
95.4
90.7
83.4
N.A.
55.6
55.3
57.1
56.3
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
100
80
100
N.A.
6.6
20
6.6
53.3
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
13.3
100
93.3
100
N.A.
13.3
20
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
7
7
7
0
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
7
0
60
0
0
20
0
7
0
0
0
% D
% Glu:
0
0
60
7
0
0
7
0
7
0
20
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
7
0
0
0
0
7
7
7
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
7
7
7
7
0
14
7
20
7
7
7
7
7
74
67
% K
% Leu:
0
7
0
0
0
7
0
0
14
14
0
60
60
0
0
% L
% Met:
0
0
0
0
7
0
7
0
7
0
0
7
0
0
0
% M
% Asn:
7
0
0
0
7
0
7
0
0
54
0
7
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
60
0
7
0
0
0
0
0
0
54
0
0
0
0
% R
% Ser:
7
0
7
60
0
0
0
0
0
0
0
0
14
0
0
% S
% Thr:
54
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% T
% Val:
0
7
0
7
60
60
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% W
% Tyr:
0
0
7
0
0
0
0
54
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _