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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT2
All Species:
19.09
Human Site:
S168
Identified Species:
38.18
UniProt:
Q99447
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99447
NP_002852.1
389
43835
S168
H
S
S
Q
E
M
S
S
E
Y
R
E
Y
A
D
Chimpanzee
Pan troglodytes
XP_511749
390
43923
S168
H
S
S
Q
E
M
S
S
E
Y
R
E
Y
A
D
Rhesus Macaque
Macaca mulatta
XP_001112535
383
42727
S168
H
S
S
Q
E
M
S
S
E
Y
R
E
Y
A
D
Dog
Lupus familis
XP_855790
354
40211
A142
S
S
E
Y
R
E
Y
A
D
S
F
G
K
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q922E4
404
45216
S168
H
S
S
Q
E
M
S
S
E
Y
R
E
Y
A
D
Rat
Rattus norvegicus
O88637
404
45201
S168
H
S
S
Q
E
M
S
S
E
Y
R
E
Y
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086220
383
43851
D165
H
S
M
E
V
T
L
D
Y
Q
K
H
Q
N
N
Zebra Danio
Brachydanio rerio
NP_001006037
397
44896
A176
H
S
N
I
D
N
A
A
Y
Q
V
H
T
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723790
381
42679
Y166
F
R
Q
G
S
A
E
Y
D
I
E
K
E
G
S
Honey Bee
Apis mellifera
XP_624319
368
42041
Y153
F
K
Q
G
D
S
E
Y
S
V
D
R
E
P
S
Nematode Worm
Caenorhab. elegans
NP_490931
370
41942
E158
H
T
Q
D
E
H
I
E
Q
H
V
E
R
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33412
323
36844
H140
V
S
T
T
E
I
I
H
R
I
L
T
K
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91
85
N.A.
87.8
88.6
N.A.
N.A.
N.A.
76
75
N.A.
60.9
63.2
55.7
N.A.
Protein Similarity:
100
99.4
92.5
87.9
N.A.
91.5
92
N.A.
N.A.
N.A.
87.6
84.3
N.A.
74
75
70.1
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
N.A.
13.3
13.3
N.A.
0
0
26.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
N.A.
33.3
46.6
N.A.
13.3
6.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
17
0
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
9
17
0
0
9
17
0
9
0
0
9
42
% D
% Glu:
0
0
9
9
59
9
17
9
42
0
9
50
17
0
0
% E
% Phe:
17
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
0
0
0
0
9
0
9
0
% G
% His:
67
0
0
0
0
9
0
9
0
9
0
17
0
0
0
% H
% Ile:
0
0
0
9
0
9
17
0
0
17
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
9
9
17
9
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% L
% Met:
0
0
9
0
0
42
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
9
0
0
0
0
0
0
0
9
17
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% P
% Gln:
0
0
25
42
0
0
0
0
9
17
0
0
9
0
0
% Q
% Arg:
0
9
0
0
9
0
0
0
9
0
42
9
9
0
9
% R
% Ser:
9
75
42
0
9
9
42
42
9
9
0
0
0
0
25
% S
% Thr:
0
9
9
9
0
9
0
0
0
0
0
9
9
0
0
% T
% Val:
9
0
0
0
9
0
0
0
0
9
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
17
17
42
0
0
42
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _