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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCYT2 All Species: 30.61
Human Site: S319 Identified Species: 61.21
UniProt: Q99447 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99447 NP_002852.1 389 43835 S319 I I P D R D G S D P Y Q E P K
Chimpanzee Pan troglodytes XP_511749 390 43923 S320 I I P D R D G S D P Y Q E P K
Rhesus Macaque Macaca mulatta XP_001112535 383 42727 P319 S S P D P Q E P K R R G I F R
Dog Lupus familis XP_855790 354 40211 S287 I V P D K D G S D P Y Q E P K
Cat Felis silvestris
Mouse Mus musculus Q922E4 404 45216 S337 I V P D R D G S D P Y Q E P K
Rat Rattus norvegicus O88637 404 45201 S337 I V P D R D G S D P Y E E P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086220 383 43851 S315 V L P D R D G S D P Y A E P K
Zebra Danio Brachydanio rerio NP_001006037 397 44896 T326 V F P D A D G T D P Y A E P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723790 381 42679 I316 I A L E N G K I D P Y A V P K
Honey Bee Apis mellifera XP_624319 368 42041 S303 I M P C E D G S D P Y I E P K
Nematode Worm Caenorhab. elegans NP_490931 370 41942 S307 N N S S V V N S S L A S I D P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33412 323 36844 Y279 S Q Y N C E K Y H I G T A V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 91 85 N.A. 87.8 88.6 N.A. N.A. N.A. 76 75 N.A. 60.9 63.2 55.7 N.A.
Protein Similarity: 100 99.4 92.5 87.9 N.A. 91.5 92 N.A. N.A. N.A. 87.6 84.3 N.A. 74 75 70.1 N.A.
P-Site Identity: 100 100 13.3 86.6 N.A. 93.3 86.6 N.A. N.A. N.A. 80 66.6 N.A. 40 73.3 6.6 N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. N.A. N.A. 93.3 80 N.A. 46.6 80 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 0 0 0 0 0 9 25 9 0 0 % A
% Cys: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 67 0 67 0 0 75 0 0 0 0 9 0 % D
% Glu: 0 0 0 9 9 9 9 0 0 0 0 9 67 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 9 67 0 0 0 9 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 59 17 0 0 0 0 0 9 0 9 0 9 17 0 0 % I
% Lys: 0 0 0 0 9 0 17 0 9 0 0 0 0 0 75 % K
% Leu: 0 9 9 0 0 0 0 0 0 9 0 0 0 0 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 9 9 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 75 0 9 0 0 9 0 75 0 0 0 75 9 % P
% Gln: 0 9 0 0 0 9 0 0 0 0 0 34 0 0 0 % Q
% Arg: 0 0 0 0 42 0 0 0 0 9 9 0 0 0 9 % R
% Ser: 17 9 9 9 0 0 0 67 9 0 0 9 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % T
% Val: 17 25 0 0 9 9 0 0 0 0 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 9 0 0 75 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _