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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCYT2 All Species: 36.36
Human Site: T157 Identified Species: 72.73
UniProt: Q99447 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99447 NP_002852.1 389 43835 T157 V G R M L L V T K A H H S S Q
Chimpanzee Pan troglodytes XP_511749 390 43923 T157 V G R M L L V T K A H H S S Q
Rhesus Macaque Macaca mulatta XP_001112535 383 42727 T157 V G R M L L V T K A H H S S Q
Dog Lupus familis XP_855790 354 40211 G131 V T K A H H S G Q E I S S E Y
Cat Felis silvestris
Mouse Mus musculus Q922E4 404 45216 T157 V G R M L L V T K A H H S S Q
Rat Rattus norvegicus O88637 404 45201 T157 V G R M L L V T K A H H S S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086220 383 43851 T154 V G R M L L M T K A H H S M E
Zebra Danio Brachydanio rerio NP_001006037 397 44896 T165 V G R M L L L T K A H H S N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723790 381 42679 T155 V G R M L L L T R N H F R Q G
Honey Bee Apis mellifera XP_624319 368 42041 T142 V G R M L L M T R Q H F K Q G
Nematode Worm Caenorhab. elegans NP_490931 370 41942 T147 V G R M L L L T K N H H T Q D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33412 323 36844 R129 G R F K V V K R T Y G V S T T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 91 85 N.A. 87.8 88.6 N.A. N.A. N.A. 76 75 N.A. 60.9 63.2 55.7 N.A.
Protein Similarity: 100 99.4 92.5 87.9 N.A. 91.5 92 N.A. N.A. N.A. 87.6 84.3 N.A. 74 75 70.1 N.A.
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. N.A. N.A. 80 80 N.A. 53.3 53.3 66.6 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. N.A. N.A. 93.3 93.3 N.A. 66.6 66.6 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 59 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 9 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 17 0 0 0 % F
% Gly: 9 84 0 0 0 0 0 9 0 0 9 0 0 0 17 % G
% His: 0 0 0 0 9 9 0 0 0 0 84 67 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % I
% Lys: 0 0 9 9 0 0 9 0 67 0 0 0 9 0 0 % K
% Leu: 0 0 0 0 84 84 25 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 84 0 0 17 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 17 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 9 0 0 0 25 42 % Q
% Arg: 0 9 84 0 0 0 0 9 17 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 0 0 0 9 75 42 0 % S
% Thr: 0 9 0 0 0 0 0 84 9 0 0 0 9 9 9 % T
% Val: 92 0 0 0 9 9 42 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _