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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT2
All Species:
36.36
Human Site:
Y126
Identified Species:
72.73
UniProt:
Q99447
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99447
NP_002852.1
389
43835
Y126
T
V
D
G
R
D
T
Y
E
E
V
K
Q
A
G
Chimpanzee
Pan troglodytes
XP_511749
390
43923
Y126
T
V
D
G
R
D
T
Y
E
E
V
K
Q
A
G
Rhesus Macaque
Macaca mulatta
XP_001112535
383
42727
Y126
T
V
D
G
R
D
T
Y
E
E
V
K
Q
A
G
Dog
Lupus familis
XP_855790
354
40211
A100
P
Y
E
E
V
K
A
A
G
R
Y
R
E
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q922E4
404
45216
Y126
T
V
D
G
R
D
T
Y
E
E
V
K
Q
A
G
Rat
Rattus norvegicus
O88637
404
45201
Y126
T
V
D
G
R
D
T
Y
E
E
V
K
Q
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086220
383
43851
Y123
T
V
D
G
K
D
T
Y
E
E
V
K
N
A
G
Zebra Danio
Brachydanio rerio
NP_001006037
397
44896
Y134
T
V
D
G
K
D
T
Y
D
E
V
K
R
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723790
381
42679
Y124
T
A
E
G
V
D
T
Y
H
L
V
K
S
A
N
Honey Bee
Apis mellifera
XP_624319
368
42041
Y111
T
A
D
G
V
D
T
Y
H
L
V
K
A
A
G
Nematode Worm
Caenorhab. elegans
NP_490931
370
41942
Y116
T
A
D
G
K
D
T
Y
Q
E
V
K
D
H
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33412
323
36844
Y98
M
D
K
Y
Q
C
Q
Y
V
V
H
G
D
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91
85
N.A.
87.8
88.6
N.A.
N.A.
N.A.
76
75
N.A.
60.9
63.2
55.7
N.A.
Protein Similarity:
100
99.4
92.5
87.9
N.A.
91.5
92
N.A.
N.A.
N.A.
87.6
84.3
N.A.
74
75
70.1
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
N.A.
86.6
73.3
N.A.
53.3
66.6
60
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
60
66.6
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
0
0
9
9
0
0
0
0
9
67
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
75
0
0
84
0
0
9
0
0
0
17
9
0
% D
% Glu:
0
0
17
9
0
0
0
0
50
67
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
84
0
0
0
0
9
0
0
9
0
0
67
% G
% His:
0
0
0
0
0
0
0
0
17
0
9
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
9
0
25
9
0
0
0
0
0
84
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
9
0
9
0
0
0
42
0
9
% Q
% Arg:
0
0
0
0
42
0
0
0
0
9
0
9
9
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
84
0
0
0
0
0
84
0
0
0
0
0
0
9
0
% T
% Val:
0
59
0
0
25
0
0
0
9
9
84
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
0
0
0
92
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _