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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT2
All Species:
34.85
Human Site:
Y258
Identified Species:
69.7
UniProt:
Q99447
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99447
NP_002852.1
389
43835
Y258
F
D
Q
E
V
N
H
Y
K
G
K
N
Y
P
I
Chimpanzee
Pan troglodytes
XP_511749
390
43923
K259
D
Q
E
V
N
H
Y
K
G
K
N
Y
P
I
M
Rhesus Macaque
Macaca mulatta
XP_001112535
383
42727
Y258
F
D
Q
E
V
N
R
Y
K
G
K
N
Y
P
I
Dog
Lupus familis
XP_855790
354
40211
Y226
F
D
Q
E
V
N
H
Y
K
G
K
N
Y
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q922E4
404
45216
Y276
F
D
Q
E
V
N
R
Y
K
G
K
N
Y
P
I
Rat
Rattus norvegicus
O88637
404
45201
Y276
F
D
Q
E
V
N
R
Y
K
G
K
N
Y
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086220
383
43851
Y254
F
D
Q
E
V
N
H
Y
K
R
K
N
Y
P
I
Zebra Danio
Brachydanio rerio
NP_001006037
397
44896
Y265
F
D
Q
E
V
N
R
Y
K
G
K
N
Y
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723790
381
42679
Y255
T
D
P
V
V
N
S
Y
K
G
S
N
Y
P
I
Honey Bee
Apis mellifera
XP_624319
368
42041
Y242
T
D
P
V
V
N
R
Y
K
Y
G
N
H
P
I
Nematode Worm
Caenorhab. elegans
NP_490931
370
41942
Y246
S
D
Q
T
V
N
Q
Y
K
G
S
N
H
P
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33412
323
36844
R218
M
G
D
I
D
Q
L
R
K
L
K
M
D
L
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91
85
N.A.
87.8
88.6
N.A.
N.A.
N.A.
76
75
N.A.
60.9
63.2
55.7
N.A.
Protein Similarity:
100
99.4
92.5
87.9
N.A.
91.5
92
N.A.
N.A.
N.A.
87.6
84.3
N.A.
74
75
70.1
N.A.
P-Site Identity:
100
0
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
66.6
53.3
66.6
N.A.
P-Site Similarity:
100
26.6
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
66.6
60
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
84
9
0
9
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
9
59
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
9
67
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
25
0
0
0
0
0
17
0
9
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
84
% I
% Lys:
0
0
0
0
0
0
0
9
92
9
67
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
9
0
0
0
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
0
0
0
0
9
84
0
0
0
0
9
84
0
0
0
% N
% Pro:
0
0
17
0
0
0
0
0
0
0
0
0
9
84
0
% P
% Gln:
0
9
67
0
0
9
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
42
9
0
9
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
9
0
0
0
17
0
0
0
0
% S
% Thr:
17
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
25
84
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
84
0
9
0
9
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _