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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHOX2B
All Species:
11.52
Human Site:
T69
Identified Species:
31.67
UniProt:
Q99453
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99453
NP_003915.2
314
31621
T69
P
G
S
C
S
L
G
T
L
R
D
H
Q
S
S
Chimpanzee
Pan troglodytes
A2T711
184
20085
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852840
314
31545
T69
P
G
S
C
S
L
G
T
L
R
D
H
Q
S
S
Cat
Felis silvestris
Mouse
Mus musculus
O35690
314
31602
T69
P
G
S
C
S
L
G
T
L
R
D
H
Q
S
S
Rat
Rattus norvegicus
Q62782
281
29507
S71
D
H
Q
P
A
P
Y
S
A
V
P
Y
K
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PVX0
317
34038
P69
E
A
A
D
K
R
G
P
R
H
C
L
P
K
G
Frog
Xenopus laevis
Q91574
335
37508
T107
E
L
G
R
S
M
D
T
C
C
S
L
A
V
S
Zebra Danio
Brachydanio rerio
O42115
453
49378
D165
S
T
L
K
F
E
E
D
V
V
K
E
E
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120833
319
33650
A84
T
T
H
S
H
A
H
A
H
H
G
A
H
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.6
N.A.
99.3
N.A.
100
53.8
N.A.
N.A.
30.9
28.9
23.8
N.A.
N.A.
38.5
N.A.
N.A.
Protein Similarity:
100
35.6
N.A.
99.6
N.A.
100
62
N.A.
N.A.
44.4
42.6
35.9
N.A.
N.A.
52
N.A.
N.A.
P-Site Identity:
100
0
N.A.
100
N.A.
100
0
N.A.
N.A.
6.6
20
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
100
N.A.
100
26.6
N.A.
N.A.
13.3
26.6
20
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
12
12
0
12
12
0
0
12
12
12
0
% A
% Cys:
0
0
0
34
0
0
0
0
12
12
12
0
0
0
12
% C
% Asp:
12
0
0
12
0
0
12
12
0
0
34
0
0
0
0
% D
% Glu:
23
0
0
0
0
12
12
0
0
0
0
12
12
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
12
% F
% Gly:
0
34
12
0
0
0
45
0
0
0
12
0
0
0
12
% G
% His:
0
12
12
0
12
0
12
0
12
23
0
34
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
12
0
0
0
0
0
12
0
12
12
0
% K
% Leu:
0
12
12
0
0
34
0
0
34
0
0
23
0
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
0
0
12
0
12
0
12
0
0
12
0
12
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
34
0
0
% Q
% Arg:
0
0
0
12
0
12
0
0
12
34
0
0
0
0
0
% R
% Ser:
12
0
34
12
45
0
0
12
0
0
12
0
0
34
45
% S
% Thr:
12
23
0
0
0
0
0
45
0
0
0
0
0
12
12
% T
% Val:
0
0
0
0
0
0
0
0
12
23
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _