KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTCH4
All Species:
7.88
Human Site:
S1849
Identified Species:
14.44
UniProt:
Q99466
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99466
NP_004548.3
2003
209622
S1849
R
A
R
T
V
S
V
S
V
P
P
H
G
G
G
Chimpanzee
Pan troglodytes
XP_518380
2003
209553
S1844
L
A
R
T
V
S
V
S
V
P
P
H
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001114248
2471
265649
S2166
T
Y
V
S
D
T
T
S
S
P
M
I
T
S
P
Dog
Lupus familis
XP_538847
1778
185807
E1643
T
A
A
R
R
L
L
E
A
G
A
N
P
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
P31695
1964
206674
L1811
Q
R
S
H
W
D
L
L
T
L
L
E
G
A
G
Rat
Rattus norvegicus
Q07008
2531
270981
G2233
G
M
P
D
T
H
L
G
I
S
H
L
N
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512292
2467
261963
S2143
K
G
Q
L
S
E
S
S
V
T
L
S
P
V
D
Chicken
Gallus gallus
XP_415420
2590
279561
N2270
Q
S
P
S
M
P
L
N
H
L
P
G
M
P
D
Frog
Xenopus laevis
P21783
2524
275106
T2120
Y
N
L
V
K
S
P
T
L
H
N
G
P
L
G
Zebra Danio
Brachydanio rerio
P46530
2437
262289
N2249
S
H
L
P
V
A
N
N
V
G
G
A
Q
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
A2237
T
S
A
A
S
K
K
A
A
N
L
N
G
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P14585
1429
157097
D1294
H
N
I
V
D
I
F
D
R
C
R
P
E
R
E
Sea Urchin
Strong. purpuratus
P10079
1064
112055
I929
C
Q
C
R
L
G
Y
I
G
V
N
C
E
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
33.6
78.1
N.A.
80.1
34
N.A.
33.4
34.4
33.4
35.9
N.A.
30.2
N.A.
22.9
23.4
Protein Similarity:
100
99.3
46.5
81.7
N.A.
85.7
45.9
N.A.
45.4
45.8
46
47.7
N.A.
40.6
N.A.
36
32
P-Site Identity:
100
93.3
13.3
6.6
N.A.
13.3
0
N.A.
13.3
6.6
13.3
20
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
93.3
26.6
20
N.A.
26.6
13.3
N.A.
26.6
46.6
26.6
33.3
N.A.
26.6
N.A.
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
16
8
0
8
0
8
16
0
8
8
0
16
8
% A
% Cys:
8
0
8
0
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
0
0
0
8
16
8
0
8
0
0
0
0
0
0
16
% D
% Glu:
0
0
0
0
0
8
0
8
0
0
0
8
16
8
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
8
0
8
8
16
8
16
31
16
39
% G
% His:
8
8
0
8
0
8
0
0
8
8
8
16
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
8
8
0
0
8
0
0
0
% I
% Lys:
8
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
16
8
8
8
31
8
8
16
24
8
0
16
0
% L
% Met:
0
8
0
0
8
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
16
0
0
0
0
8
16
0
8
16
16
8
8
8
% N
% Pro:
0
0
16
8
0
8
8
0
0
24
24
8
24
8
8
% P
% Gln:
16
8
8
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
8
8
16
16
8
0
0
0
8
0
8
0
0
8
0
% R
% Ser:
8
16
8
16
16
24
8
31
8
8
0
8
0
8
0
% S
% Thr:
24
0
0
16
8
8
8
8
8
8
0
0
8
0
0
% T
% Val:
0
0
8
16
24
0
16
0
31
8
0
0
0
16
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _