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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTCH4
All Species:
14.24
Human Site:
S1980
Identified Species:
26.11
UniProt:
Q99466
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99466
NP_004548.3
2003
209622
S1980
T
P
S
P
E
R
G
S
P
Q
L
D
C
G
P
Chimpanzee
Pan troglodytes
XP_518380
2003
209553
S1975
T
P
S
P
E
R
G
S
P
Q
L
D
C
G
S
Rhesus Macaque
Macaca mulatta
XP_001114248
2471
265649
T2401
S
S
N
A
A
E
R
T
P
S
H
S
G
H
L
Dog
Lupus familis
XP_538847
1778
185807
S1771
S
N
K
T
G
R
G
S
A
E
S
A
E
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P31695
1964
206674
S1941
T
P
S
P
E
R
G
S
P
Q
V
A
W
G
L
Rat
Rattus norvegicus
Q07008
2531
270981
D2417
S
G
E
P
S
Q
A
D
V
Q
P
L
G
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512292
2467
261963
G2311
F
H
L
L
P
K
G
G
G
A
Q
A
A
G
L
Chicken
Gallus gallus
XP_415420
2590
279561
G2424
M
Q
Q
M
Q
Q
P
G
M
Q
P
Q
P
G
M
Frog
Xenopus laevis
P21783
2524
275106
T2277
L
N
A
S
S
P
N
T
I
M
S
N
G
S
M
Zebra Danio
Brachydanio rerio
P46530
2437
262289
F2393
Q
Q
V
P
D
H
P
F
L
T
P
S
A
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
S2438
S
P
H
A
Y
L
G
S
P
S
P
A
K
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P14585
1429
157097
Y1422
Q
N
E
P
M
T
R
Y
S
E
P
A
H
Y
F
Sea Urchin
Strong. purpuratus
P10079
1064
112055
S1057
K
W
T
R
Y
E
Q
S
I
A
P
Q
P
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
33.6
78.1
N.A.
80.1
34
N.A.
33.4
34.4
33.4
35.9
N.A.
30.2
N.A.
22.9
23.4
Protein Similarity:
100
99.3
46.5
81.7
N.A.
85.7
45.9
N.A.
45.4
45.8
46
47.7
N.A.
40.6
N.A.
36
32
P-Site Identity:
100
93.3
6.6
20
N.A.
73.3
13.3
N.A.
13.3
13.3
0
13.3
N.A.
26.6
N.A.
6.6
6.6
P-Site Similarity:
100
93.3
26.6
33.3
N.A.
80
26.6
N.A.
20
26.6
20
20
N.A.
33.3
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
8
0
8
0
8
16
0
39
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
16
0
8
0
% D
% Glu:
0
0
16
0
24
16
0
0
0
16
0
0
8
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
8
0
47
16
8
0
0
0
24
47
0
% G
% His:
0
8
8
0
0
8
0
0
0
0
8
0
8
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
0
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
8
8
0
8
0
0
8
0
16
8
0
0
31
% L
% Met:
8
0
0
8
8
0
0
0
8
8
0
0
0
0
16
% M
% Asn:
0
24
8
0
0
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
31
0
47
8
8
16
0
39
0
47
0
16
8
8
% P
% Gln:
16
16
8
0
8
16
8
0
0
39
8
16
0
0
0
% Q
% Arg:
0
0
0
8
0
31
16
0
0
0
0
0
0
0
8
% R
% Ser:
31
8
24
8
16
0
0
47
8
16
16
16
0
24
24
% S
% Thr:
24
0
8
8
0
8
0
16
0
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
16
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _