KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTCH4
All Species:
39.09
Human Site:
T1769
Identified Species:
71.67
UniProt:
Q99466
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99466
NP_004548.3
2003
209622
T1769
A
Q
D
N
R
E
Q
T
P
L
F
L
A
A
R
Chimpanzee
Pan troglodytes
XP_518380
2003
209553
T1764
A
Q
D
N
R
E
Q
T
P
L
F
L
A
A
R
Rhesus Macaque
Macaca mulatta
XP_001114248
2471
265649
T2012
M
Q
D
N
K
E
E
T
P
L
F
L
A
A
R
Dog
Lupus familis
XP_538847
1778
185807
A1596
E
S
R
T
F
Q
G
A
W
L
G
S
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P31695
1964
206674
T1764
A
Q
D
S
R
E
Q
T
P
L
F
L
A
A
R
Rat
Rattus norvegicus
Q07008
2531
270981
T2053
M
Q
N
N
K
E
E
T
P
L
F
L
A
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512292
2467
261963
T2008
M
Q
D
N
K
E
E
T
P
L
F
L
A
A
R
Chicken
Gallus gallus
XP_415420
2590
279561
T2102
M
Q
N
N
K
E
E
T
P
L
F
L
A
A
R
Frog
Xenopus laevis
P21783
2524
275106
T2060
M
Q
N
N
K
E
E
T
S
L
F
L
A
A
R
Zebra Danio
Brachydanio rerio
P46530
2437
262289
T2051
L
Q
N
N
K
E
E
T
P
L
F
L
A
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
T2086
A
Q
D
D
K
D
E
T
P
L
F
L
A
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P14585
1429
157097
L1247
D
G
K
T
P
I
M
L
A
A
Q
E
G
R
I
Sea Urchin
Strong. purpuratus
P10079
1064
112055
Y882
C
V
N
V
G
A
D
Y
V
C
E
C
V
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
33.6
78.1
N.A.
80.1
34
N.A.
33.4
34.4
33.4
35.9
N.A.
30.2
N.A.
22.9
23.4
Protein Similarity:
100
99.3
46.5
81.7
N.A.
85.7
45.9
N.A.
45.4
45.8
46
47.7
N.A.
40.6
N.A.
36
32
P-Site Identity:
100
100
80
6.6
N.A.
93.3
73.3
N.A.
80
73.3
66.6
73.3
N.A.
73.3
N.A.
0
0
P-Site Similarity:
100
100
93.3
13.3
N.A.
100
93.3
N.A.
93.3
93.3
86.6
93.3
N.A.
100
N.A.
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
0
0
8
0
8
8
8
0
0
77
77
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
8
0
47
8
0
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
70
54
0
0
0
8
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
77
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
8
0
0
0
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
54
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
8
0
85
0
77
0
0
0
% L
% Met:
39
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
39
62
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
70
0
0
0
8
8
8
% P
% Gln:
0
77
0
0
0
8
24
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
0
24
0
0
0
0
0
0
0
0
8
77
% R
% Ser:
0
8
0
8
0
0
0
0
8
0
0
8
0
0
0
% S
% Thr:
0
0
0
16
0
0
0
77
0
0
0
0
0
0
0
% T
% Val:
0
8
0
8
0
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _