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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTCH4
All Species:
1.82
Human Site:
T1910
Identified Species:
3.33
UniProt:
Q99466
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99466
NP_004548.3
2003
209622
T1910
V
G
A
G
G
G
P
T
P
R
G
R
R
F
S
Chimpanzee
Pan troglodytes
XP_518380
2003
209553
P1905
V
G
A
G
G
G
P
P
P
R
G
R
R
F
S
Rhesus Macaque
Macaca mulatta
XP_001114248
2471
265649
V2231
L
L
S
H
H
H
I
V
P
P
S
S
G
S
A
Dog
Lupus familis
XP_538847
1778
185807
D1703
A
A
R
L
A
V
E
D
L
V
E
E
L
I
A
Cat
Felis silvestris
Mouse
Mus musculus
P31695
1964
206674
K1871
D
L
G
A
R
G
G
K
V
Y
A
R
C
R
S
Rat
Rattus norvegicus
Q07008
2531
270981
E2299
A
S
L
N
G
Q
C
E
W
L
P
R
L
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512292
2467
261963
P2227
L
L
S
H
R
L
A
P
P
G
G
G
G
G
S
Chicken
Gallus gallus
XP_415420
2590
279561
G2339
G
G
A
A
G
L
S
G
Q
C
D
W
L
S
R
Frog
Xenopus laevis
P21783
2524
275106
T2182
K
K
S
Q
D
G
K
T
T
L
L
D
S
G
S
Zebra Danio
Brachydanio rerio
P46530
2437
262289
A2317
M
I
A
H
Q
N
M
A
P
M
Q
H
Q
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
N2319
P
L
A
N
G
N
P
N
T
G
A
K
Q
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P14585
1429
157097
T1354
P
P
P
S
D
G
S
T
S
T
P
S
P
Q
H
Sea Urchin
Strong. purpuratus
P10079
1064
112055
N989
V
V
V
G
Y
A
S
N
N
Y
D
F
P
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
33.6
78.1
N.A.
80.1
34
N.A.
33.4
34.4
33.4
35.9
N.A.
30.2
N.A.
22.9
23.4
Protein Similarity:
100
99.3
46.5
81.7
N.A.
85.7
45.9
N.A.
45.4
45.8
46
47.7
N.A.
40.6
N.A.
36
32
P-Site Identity:
100
93.3
6.6
0
N.A.
20
13.3
N.A.
20
20
20
13.3
N.A.
20
N.A.
13.3
13.3
P-Site Similarity:
100
93.3
26.6
6.6
N.A.
20
20
N.A.
33.3
20
26.6
26.6
N.A.
33.3
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
39
16
8
8
8
8
0
0
16
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% C
% Asp:
8
0
0
0
16
0
0
8
0
0
16
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
8
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
16
8
% F
% Gly:
8
24
8
24
39
39
8
8
0
16
24
8
16
16
0
% G
% His:
0
0
0
24
8
8
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
8
% I
% Lys:
8
8
0
0
0
0
8
8
0
0
0
8
0
0
0
% K
% Leu:
16
31
8
8
0
16
0
0
8
16
8
0
24
0
0
% L
% Met:
8
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
16
0
16
8
0
0
0
0
8
8
% N
% Pro:
16
8
8
0
0
0
24
16
39
8
16
0
16
8
8
% P
% Gln:
0
0
0
8
8
8
0
0
8
0
8
0
16
16
0
% Q
% Arg:
0
0
8
0
16
0
0
0
0
16
0
31
16
8
8
% R
% Ser:
0
8
24
8
0
0
24
0
8
0
8
16
8
24
39
% S
% Thr:
0
0
0
0
0
0
0
24
16
8
0
0
0
0
0
% T
% Val:
24
8
8
0
0
8
0
8
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _