KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTCH4
All Species:
5.76
Human Site:
T1946
Identified Species:
10.56
UniProt:
Q99466
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99466
NP_004548.3
2003
209622
T1946
G
R
G
G
R
V
S
T
D
D
W
P
C
D
W
Chimpanzee
Pan troglodytes
XP_518380
2003
209553
T1941
G
R
G
G
R
V
S
T
D
D
W
P
C
D
W
Rhesus Macaque
Macaca mulatta
XP_001114248
2471
265649
Q2367
Q
Q
D
G
Q
V
A
Q
T
I
L
P
A
Y
H
Dog
Lupus familis
XP_538847
1778
185807
A1737
A
A
V
N
N
A
R
A
A
R
C
L
L
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P31695
1964
206674
Q1907
R
R
G
A
R
A
S
Q
D
D
W
P
R
D
W
Rat
Rattus norvegicus
Q07008
2531
270981
P2383
P
Q
N
L
Q
I
Q
P
Q
N
L
Q
P
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512292
2467
261963
A2277
E
G
P
C
P
S
A
A
P
P
T
G
P
G
Q
Chicken
Gallus gallus
XP_415420
2590
279561
S2390
H
N
G
L
P
S
T
S
L
S
Q
M
M
S
Y
Frog
Xenopus laevis
P21783
2524
275106
I2243
S
Q
L
G
M
N
H
I
N
M
A
T
K
Q
E
Zebra Danio
Brachydanio rerio
P46530
2437
262289
P2359
Q
D
S
Q
R
M
A
P
P
I
S
S
T
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
G2404
G
L
S
G
A
G
N
G
N
S
H
E
Q
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P14585
1429
157097
E1388
Q
T
E
A
G
S
S
E
A
F
Q
P
Q
C
G
Sea Urchin
Strong. purpuratus
P10079
1064
112055
V1023
H
L
C
D
G
E
E
V
L
Y
T
T
W
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
33.6
78.1
N.A.
80.1
34
N.A.
33.4
34.4
33.4
35.9
N.A.
30.2
N.A.
22.9
23.4
Protein Similarity:
100
99.3
46.5
81.7
N.A.
85.7
45.9
N.A.
45.4
45.8
46
47.7
N.A.
40.6
N.A.
36
32
P-Site Identity:
100
100
20
0
N.A.
66.6
0
N.A.
0
6.6
6.6
6.6
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
100
40
0
N.A.
66.6
26.6
N.A.
6.6
26.6
20
26.6
N.A.
26.6
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
16
8
16
24
16
16
0
8
0
8
0
8
% A
% Cys:
0
0
8
8
0
0
0
0
0
0
8
0
16
8
0
% C
% Asp:
0
8
8
8
0
0
0
0
24
24
0
0
0
24
0
% D
% Glu:
8
0
8
0
0
8
8
8
0
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
24
8
31
39
16
8
0
8
0
0
0
8
0
16
8
% G
% His:
16
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
8
0
16
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
16
8
16
0
0
0
0
16
0
16
8
8
0
8
% L
% Met:
0
0
0
0
8
8
0
0
0
8
0
8
8
0
0
% M
% Asn:
0
8
8
8
8
8
8
0
16
8
0
0
0
0
8
% N
% Pro:
8
0
8
0
16
0
0
16
16
8
0
39
16
8
0
% P
% Gln:
24
24
0
8
16
0
8
16
8
0
16
8
16
24
8
% Q
% Arg:
8
24
0
0
31
0
8
0
0
8
0
0
8
0
0
% R
% Ser:
8
0
16
0
0
24
31
8
0
16
8
8
0
8
8
% S
% Thr:
0
8
0
0
0
0
8
16
8
0
16
16
8
0
0
% T
% Val:
0
0
8
0
0
24
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
24
0
8
0
24
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _