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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PFDN5 All Species: 45.45
Human Site: Y71 Identified Species: 83.33
UniProt: Q99471 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99471 NP_002615.2 154 17328 Y71 V P L T S S M Y V P G K L H D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534790 257 28990 Y174 V P L T S S M Y V P E K L H D
Cat Felis silvestris
Mouse Mus musculus Q9WU28 154 17338 Y71 V P L T S S M Y V P G K L H D
Rat Rattus norvegicus NP_001100264 154 17308 Y71 V P L T S S M Y V P G K L H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516164 60 6929
Chicken Gallus gallus
Frog Xenopus laevis NP_001088120 152 16852 Y71 V P L T S S M Y V P G T L N D
Zebra Danio Brachydanio rerio NP_001104665 153 17166 Y69 V P L T S S M Y V P G K L H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCZ8 168 19059 Y80 V P L T S S M Y V P G R V K D
Honey Bee Apis mellifera XP_395405 157 17738 Y81 V P L T G S M Y V V G K L V E
Nematode Worm Caenorhab. elegans Q21993 152 17133 Y74 I P L S E S L Y I R A E L S D
Sea Urchin Strong. purpuratus XP_785869 155 17778 Y73 V P L T S S L Y V P G K L Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P57742 151 16391 Y74 V P L T A S L Y V P G T L D E
Baker's Yeast Sacchar. cerevisiae Q04493 163 18337 Y73 V P A S A S L Y I P G K I V D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 58.3 N.A. 99.3 98.6 N.A. 34.4 N.A. 81.8 79.8 N.A. 35.7 44.5 31.8 58
Protein Similarity: 100 N.A. N.A. 59.1 N.A. 99.3 99.3 N.A. 36.3 N.A. 92.8 90.2 N.A. 58.9 63.6 55.1 78
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 0 N.A. 86.6 100 N.A. 80 73.3 40 86.6
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 0 N.A. 93.3 100 N.A. 93.3 80 73.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 38.3 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. 61.6 63.1 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 16 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 77 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 8 8 0 0 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 77 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 39 0 % H
% Ile: 8 0 0 0 0 0 0 0 16 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 62 0 8 0 % K
% Leu: 0 0 85 0 0 0 31 0 0 0 0 0 77 0 0 % L
% Met: 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 93 0 0 0 0 0 0 0 77 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % R
% Ser: 0 0 0 16 62 93 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 77 0 0 0 0 0 0 0 16 0 0 0 % T
% Val: 85 0 0 0 0 0 0 0 77 8 0 0 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _