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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDO
All Species:
2.73
Human Site:
S219
Identified Species:
6.67
UniProt:
Q99489
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99489
NP_003640.2
341
37535
S219
E
H
F
I
R
D
G
S
G
L
T
Y
I
Y
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103664
347
39422
Y224
H
E
P
E
S
G
I
Y
N
S
P
Y
I
I
P
Dog
Lupus familis
XP_532262
356
38455
A219
K
H
F
I
R
E
G
A
G
L
T
Y
V
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q922Z0
341
37528
G219
K
H
F
I
R
D
G
G
G
L
T
Y
V
Y
P
Rat
Rattus norvegicus
O35078
346
38802
Y223
H
D
P
S
L
G
I
Y
N
S
P
Y
I
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520869
342
37920
N220
S
H
F
I
R
D
G
N
G
L
T
Y
I
Y
P
Chicken
Gallus gallus
XP_001234269
342
37475
N220
K
N
F
I
R
D
G
N
G
L
T
Y
I
Y
P
Frog
Xenopus laevis
NP_001090031
347
39281
Y224
H
D
L
K
T
G
V
Y
T
T
P
Y
I
I
P
Zebra Danio
Brachydanio rerio
XP_002665186
338
37951
D219
K
N
F
I
R
D
G
D
G
N
T
Y
I
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95XG9
322
36099
P203
Q
I
L
K
V
S
C
P
R
V
K
H
F
F
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
39.4
69
N.A.
80.3
40.7
N.A.
68.1
64
41.5
53.6
N.A.
N.A.
N.A.
38.1
N.A.
Protein Similarity:
100
N.A.
58.7
80.3
N.A.
86.8
60.4
N.A.
82.1
80.9
59.9
73.6
N.A.
N.A.
N.A.
56.8
N.A.
P-Site Identity:
100
N.A.
20
73.3
N.A.
80
20
N.A.
86.6
80
20
73.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
20
100
N.A.
93.3
20
N.A.
93.3
100
20
86.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
50
0
10
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
60
0
0
0
0
0
0
0
0
0
10
10
0
% F
% Gly:
0
0
0
0
0
30
60
10
60
0
0
0
0
0
0
% G
% His:
30
40
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
0
60
0
0
20
0
0
0
0
0
70
30
10
% I
% Lys:
40
0
0
20
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
20
0
10
0
0
0
0
50
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
20
20
10
0
0
0
0
0
% N
% Pro:
0
0
20
0
0
0
0
10
0
0
30
0
0
0
90
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
60
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
0
10
10
10
0
10
0
20
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
10
10
60
0
0
0
0
% T
% Val:
0
0
0
0
10
0
10
0
0
10
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
0
0
90
0
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _