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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDO All Species: 25.45
Human Site: Y146 Identified Species: 62.22
UniProt: Q99489 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99489 NP_003640.2 341 37535 Y146 L K C E C P A Y L P W L E K R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103664 347 39422 Y144 L I L E G K N Y L Q W L T E R
Dog Lupus familis XP_532262 356 38455 Y146 L K C E S S T Y L S W L E K R
Cat Felis silvestris
Mouse Mus musculus Q922Z0 341 37528 Y146 L K C E T S A Y L P W L E R R
Rat Rattus norvegicus O35078 346 38802 L144 L L E G K S Y L S W L T E R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520869 342 37920 Y147 L K C D S L F Y L P W L M K R
Chicken Gallus gallus XP_001234269 342 37475 Y147 L K C D C P P Y L L W L E K R
Frog Xenopus laevis NP_001090031 347 39281 Y144 I M I E G K H Y L P W M M K R
Zebra Danio Brachydanio rerio XP_002665186 338 37951 Y146 L K C E C L S Y L P W L E Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95XG9 322 36099 Y140 W Y L E P T P Y I K W C T D K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 39.4 69 N.A. 80.3 40.7 N.A. 68.1 64 41.5 53.6 N.A. N.A. N.A. 38.1 N.A.
Protein Similarity: 100 N.A. 58.7 80.3 N.A. 86.8 60.4 N.A. 82.1 80.9 59.9 73.6 N.A. N.A. N.A. 56.8 N.A.
P-Site Identity: 100 N.A. 46.6 73.3 N.A. 80 13.3 N.A. 66.6 80 46.6 80 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 N.A. 53.3 73.3 N.A. 86.6 20 N.A. 73.3 86.6 60 93.3 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 60 0 30 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 20 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 10 70 0 0 0 0 0 0 0 0 60 10 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 20 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 10 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 60 0 0 10 20 0 0 0 10 0 0 0 50 10 % K
% Leu: 80 10 20 0 0 20 0 10 80 10 10 70 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 10 20 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 20 20 0 0 50 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 80 % R
% Ser: 0 0 0 0 20 30 10 0 10 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 10 10 0 0 0 0 10 20 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 10 90 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 90 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _