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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF2
All Species:
17.58
Human Site:
S177
Identified Species:
35.15
UniProt:
Q99496
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99496
NP_009143.1
336
37655
S177
A
E
D
N
G
D
S
S
H
C
S
N
A
S
T
Chimpanzee
Pan troglodytes
XP_514057
377
41465
L211
K
H
N
N
Q
Q
A
L
S
H
S
I
E
E
G
Rhesus Macaque
Macaca mulatta
Q8WMN5
377
39081
G207
S
E
D
S
G
D
R
G
G
T
L
G
G
G
T
Dog
Lupus familis
XP_859868
264
29237
T112
S
H
C
S
N
A
S
T
H
S
N
Q
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ4
336
37605
S177
A
E
D
N
G
D
S
S
H
C
S
N
A
S
T
Rat
Rattus norvegicus
Q4KLY4
308
34224
L156
K
I
Q
A
M
N
R
L
Q
R
G
K
K
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422295
336
37573
S177
A
E
D
N
G
D
S
S
H
C
S
N
A
S
T
Frog
Xenopus laevis
Q66J69
344
38348
S179
E
D
N
C
D
S
R
S
H
V
S
N
P
S
V
Zebra Danio
Brachydanio rerio
Q803I4
336
37521
S177
A
E
D
N
G
D
S
S
H
C
S
N
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB08
435
47237
N243
A
A
P
S
S
S
A
N
S
G
A
S
T
S
A
Honey Bee
Apis mellifera
XP_393984
403
44539
E186
R
K
N
A
N
E
S
E
N
A
S
N
A
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788976
652
73333
A490
A
Q
R
V
P
P
K
A
M
K
R
P
R
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
53.8
77.9
N.A.
99.6
90.4
N.A.
N.A.
97.9
71.2
89.2
N.A.
42.9
51.3
N.A.
20.2
Protein Similarity:
100
81.1
66
78.2
N.A.
100
91
N.A.
N.A.
99.1
80.2
93.4
N.A.
56
65.7
N.A.
33.5
P-Site Identity:
100
13.3
33.3
13.3
N.A.
100
0
N.A.
N.A.
100
33.3
93.3
N.A.
13.3
26.6
N.A.
6.6
P-Site Similarity:
100
26.6
46.6
46.6
N.A.
100
6.6
N.A.
N.A.
100
46.6
93.3
N.A.
46.6
66.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
9
0
17
0
9
17
9
0
9
9
0
42
9
9
% A
% Cys:
0
0
9
9
0
0
0
0
0
34
0
0
0
0
0
% C
% Asp:
0
9
42
0
9
42
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
42
0
0
0
9
0
9
0
0
0
0
17
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
42
0
0
9
9
9
9
9
9
9
17
% G
% His:
0
17
0
0
0
0
0
0
50
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
17
9
0
0
0
0
9
0
0
9
0
9
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
17
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
25
42
17
9
0
9
9
0
9
50
0
0
0
% N
% Pro:
0
0
9
0
9
9
0
0
0
0
0
9
9
0
0
% P
% Gln:
0
9
9
0
9
9
0
0
9
0
0
9
0
9
9
% Q
% Arg:
9
0
9
0
0
0
25
0
0
9
9
0
9
0
0
% R
% Ser:
17
0
0
25
9
17
50
42
17
9
59
9
0
50
17
% S
% Thr:
0
0
0
0
0
0
0
9
0
9
0
0
9
17
34
% T
% Val:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _