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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF2 All Species: 13.33
Human Site: T199 Identified Species: 26.67
UniProt: Q99496 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99496 NP_009143.1 336 37655 T199 P S N K R T K T S D D S G L E
Chimpanzee Pan troglodytes XP_514057 377 41465 Q233 R L Q R G K K Q Q I E N G S G
Rhesus Macaque Macaca mulatta Q8WMN5 377 39081 P229 G A P S P P E P G G E I E L V
Dog Lupus familis XP_859868 264 29237 E134 T S D D S G L E L D N N N A T
Cat Felis silvestris
Mouse Mus musculus Q9CQJ4 336 37605 T199 P S N K R T K T S D D S G L E
Rat Rattus norvegicus Q4KLY4 308 34224 H178 E D N G D S S H C S N A S T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422295 336 37573 T199 P S N K R T K T S D D S G L E
Frog Xenopus laevis Q66J69 344 38348 A201 P S R K R S R A S E D S G A E
Zebra Danio Brachydanio rerio Q803I4 336 37521 T199 P S I K R T K T S D D S G L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VB08 435 47237 R265 A S N P P S V R S T P S P V P
Honey Bee Apis mellifera XP_393984 403 44539 A208 S A P A T P N A T N A A N Q S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788976 652 73333 G512 D V E G E I E G E G S L D M P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.9 53.8 77.9 N.A. 99.6 90.4 N.A. N.A. 97.9 71.2 89.2 N.A. 42.9 51.3 N.A. 20.2
Protein Similarity: 100 81.1 66 78.2 N.A. 100 91 N.A. N.A. 99.1 80.2 93.4 N.A. 56 65.7 N.A. 33.5
P-Site Identity: 100 13.3 6.6 13.3 N.A. 100 6.6 N.A. N.A. 100 60 86.6 N.A. 26.6 0 N.A. 0
P-Site Similarity: 100 33.3 26.6 33.3 N.A. 100 26.6 N.A. N.A. 100 80 93.3 N.A. 40 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 0 9 0 0 0 17 0 0 9 17 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 9 9 9 9 9 0 0 0 0 42 42 0 9 0 9 % D
% Glu: 9 0 9 0 9 0 17 9 9 9 17 0 9 0 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 17 9 9 0 9 9 17 0 0 50 0 9 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % H
% Ile: 0 0 9 0 0 9 0 0 0 9 0 9 0 0 0 % I
% Lys: 0 0 0 42 0 9 42 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 0 0 9 0 9 0 0 9 0 42 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 42 0 0 0 9 0 0 9 17 17 17 0 0 % N
% Pro: 42 0 17 9 17 17 0 9 0 0 9 0 9 0 17 % P
% Gln: 0 0 9 0 0 0 0 9 9 0 0 0 0 9 0 % Q
% Arg: 9 0 9 9 42 0 9 9 0 0 0 0 0 0 0 % R
% Ser: 9 59 0 9 9 25 9 0 50 9 9 50 9 9 9 % S
% Thr: 9 0 0 0 9 34 0 34 9 9 0 0 0 9 9 % T
% Val: 0 9 0 0 0 0 9 0 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _