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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF2
All Species:
10
Human Site:
T285
Identified Species:
20
UniProt:
Q99496
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99496
NP_009143.1
336
37655
T285
S
N
Q
M
N
L
D
T
A
S
E
K
Q
Y
T
Chimpanzee
Pan troglodytes
XP_514057
377
41465
N324
R
Y
I
K
T
S
G
N
A
T
V
D
H
L
S
Rhesus Macaque
Macaca mulatta
Q8WMN5
377
39081
G326
P
A
L
P
S
L
E
G
V
S
E
K
Q
Y
T
Dog
Lupus familis
XP_859868
264
29237
A214
N
Q
M
N
L
D
T
A
S
E
K
Q
Y
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ4
336
37605
T285
S
N
Q
M
N
L
D
T
A
S
E
K
Q
Y
T
Rat
Rattus norvegicus
Q4KLY4
308
34224
H258
S
G
N
A
T
V
D
H
L
S
K
Y
L
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422295
336
37573
T285
S
N
Q
M
N
L
D
T
A
S
E
K
Q
Y
T
Frog
Xenopus laevis
Q66J69
344
38348
E291
A
E
G
V
T
L
G
E
V
S
E
K
Q
Y
T
Zebra Danio
Brachydanio rerio
Q803I4
336
37521
A285
A
S
P
I
N
V
E
A
A
S
E
K
Q
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB08
435
47237
Y370
T
V
D
H
L
S
K
Y
L
A
M
R
L
T
L
Honey Bee
Apis mellifera
XP_393984
403
44539
N329
R
Y
I
K
T
T
A
N
A
T
V
D
H
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788976
652
73333
F592
N
E
G
G
C
G
E
F
T
I
F
I
S
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
53.8
77.9
N.A.
99.6
90.4
N.A.
N.A.
97.9
71.2
89.2
N.A.
42.9
51.3
N.A.
20.2
Protein Similarity:
100
81.1
66
78.2
N.A.
100
91
N.A.
N.A.
99.1
80.2
93.4
N.A.
56
65.7
N.A.
33.5
P-Site Identity:
100
6.6
46.6
0
N.A.
100
20
N.A.
N.A.
100
46.6
53.3
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
20
60
26.6
N.A.
100
33.3
N.A.
N.A.
100
60
86.6
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
9
0
0
9
17
50
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
34
0
0
0
0
17
0
0
0
% D
% Glu:
0
17
0
0
0
0
25
9
0
9
50
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% F
% Gly:
0
9
17
9
0
9
17
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
9
0
0
0
0
17
0
0
% H
% Ile:
0
0
17
9
0
0
0
0
0
9
0
9
0
0
9
% I
% Lys:
0
0
0
17
0
0
9
0
0
0
17
50
0
0
0
% K
% Leu:
0
0
9
0
17
42
0
0
17
0
0
0
17
17
9
% L
% Met:
0
0
9
25
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
17
25
9
9
34
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
9
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
25
0
0
0
0
0
0
0
0
9
50
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
34
9
0
0
9
17
0
0
9
59
0
0
9
0
17
% S
% Thr:
9
0
0
0
34
9
9
25
9
17
0
0
0
25
50
% T
% Val:
0
9
0
9
0
17
0
0
17
0
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
9
0
0
0
9
9
50
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _