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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
S1PR3
All Species:
15.76
Human Site:
Y22
Identified Species:
34.67
UniProt:
Q99500
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99500
NP_005217.2
378
42250
Y22
N
E
T
L
R
E
H
Y
Q
Y
V
G
K
L
A
Chimpanzee
Pan troglodytes
XP_520117
378
42218
Y22
N
E
T
L
R
E
H
Y
Q
Y
V
G
K
L
A
Rhesus Macaque
Macaca mulatta
XP_001107778
331
36908
Y22
S
V
S
D
Y
V
N
Y
D
I
I
V
R
H
Y
Dog
Lupus familis
XP_541315
382
42671
Y26
T
E
T
L
H
E
H
Y
N
Y
V
G
K
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0U9
378
42252
Y22
N
D
T
L
R
E
H
Y
D
Y
V
G
K
L
A
Rat
Rattus norvegicus
P48303
383
42727
Y23
Q
V
S
D
Y
G
N
Y
D
I
I
V
R
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520197
378
41947
I24
Y
V
N
Y
D
I
I
I
R
H
Y
N
Y
T
G
Chicken
Gallus gallus
XP_428818
380
42633
H27
M
D
S
L
I
V
L
H
Y
N
Y
T
G
K
L
Frog
Xenopus laevis
Q9PU17
366
41345
G40
A
F
F
Y
N
R
S
G
K
Y
L
A
T
E
W
Zebra Danio
Brachydanio rerio
Q9DDK4
362
40583
A26
H
K
D
P
G
L
K
A
D
S
V
V
F
I
I
Tiger Blowfish
Takifugu rubipres
Q9PUQ8
384
42694
T22
G
K
L
D
H
R
P
T
V
G
T
S
P
G
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
45.5
86.6
N.A.
87.5
51.1
N.A.
52.3
76
34.9
51.8
61.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
60.8
90.8
N.A.
92.3
70.5
N.A.
70.3
83.9
57.9
69
73.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
73.3
N.A.
86.6
6.6
N.A.
0
6.6
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
73.3
N.A.
93.3
33.3
N.A.
13.3
26.6
20
26.6
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
10
28
10
0
0
0
37
0
0
0
0
0
0
% D
% Glu:
0
28
0
0
0
37
0
0
0
0
0
0
0
10
10
% E
% Phe:
0
10
10
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
10
10
0
10
0
10
0
37
10
10
10
% G
% His:
10
0
0
0
19
0
37
10
0
10
0
0
0
19
0
% H
% Ile:
0
0
0
0
10
10
10
10
0
19
19
0
0
10
10
% I
% Lys:
0
19
0
0
0
0
10
0
10
0
0
0
37
10
0
% K
% Leu:
0
0
10
46
0
10
10
0
0
0
10
0
0
37
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
28
0
10
0
10
0
19
0
10
10
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
28
19
0
0
10
0
0
0
19
0
0
% R
% Ser:
10
0
28
0
0
0
10
0
0
10
0
10
0
0
0
% S
% Thr:
10
0
37
0
0
0
0
10
0
0
10
10
10
10
10
% T
% Val:
0
28
0
0
0
19
0
0
10
0
46
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
19
19
0
0
55
10
46
19
0
10
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _